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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CVT-6883
Molecular formula	C21H21F3N6O2
IUPAC name	3-ethyl-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]pyrazol-4-yl]-7H-purine-2,6-dione
Molecular weight	446.434
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.2
Synonyms	CHEMBL260933 GS-6201 UNII-67CKV7X08G 222C836 752222-83-6 Kinome_3621 3-ethyl-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]pyrazol-4-yl]-7H-purine-2,6-dione AOB4675 NCGC00345800-05 BDBM50236738 CTV-6883 GS-6201 (CVT6883) ZINC29055563 3-ethyl-1-propyl-8-(1-(3-(trifluoromethyl)benzyl)-1H-pyrazol-4-yl)-1H-purine-2,6(3H,7H)-dione 8-(1-(3-(trifluoromethyl)benzyl)-1H-pyrazol-4-yl)-3-ethyl-1-propyl-1H-purine-2,6(3H,7H)-dione CVT6883 MolPort-035-765-814 3-Ethyl-3,9-dihydro-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-1H-purine-2,6-dione API0004749 GS 6201 SCHEMBL238694 1H-Purine-2,6-dione, 3-ethyl-3,9-dihydro-1-propyl-8-(1-((3-(trifluoromethyl)phenyl)methyl)-1H-pyrazol-4-yl)- 67CKV7X08G CVT 6883 GTPL5615 3-Ethyl-1-propyl-8-(1-(3-trifluoromethylbenzyl)-1H-pyrazol-4-yl)-3,7-dihydropurine-2,6-dione AKOS024458311 D0G4CF NCGC00345800-01 AS-16811 [ Show all ]
Inchi Key	KOYXXLLNCXWUNF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H21F3N6O2/c1-3-8-30-19(31)16-18(29(4-2)20(30)32)27-17(26-16)14-10-25-28(12-14)11-13-6-5-7-15(9-13)21(22,23)24/h5-7,9-10,12H,3-4,8,11H2,1-2H3,(H,26,27)
PubChem CID	11270783
ChEMBL	CHEMBL260933
IUPHAR	5615
BindingDB	50236738
DrugBank	DB05936
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
174528	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
174527	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
174529	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
174531	Adenosine receptor A2b	Q60614	Adora2b	Mus musculus (Mouse)	332
174530	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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