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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000390375
Molecular formula	C17H18Cl2N4O3
IUPAC name	2-(4,5-dichloro-6-oxopyridazin-1-yl)-N-[2-(2-ethylanilino)-2-oxoethyl]-N-methylacetamide
Molecular weight	397.256
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.4
Synonyms	2-[2-(4,5-dichloro-6-oxo-1,6-dihydropyridazin-1-yl)-N-methylacetamido]-N-(2-ethylphenyl)acetamide CHEMBL1374788 ZINC3464950 923799-20-6 MCULE-1395490520 2-(4,5-dichloro-6-oxo-1-pyridazinyl)-N-[2-(2-ethylanilino)-2-oxoethyl]-N-methylacetamide BDBM42061 SMR000255342 2-[4,5-bis(chloranyl)-6-oxidanylidene-pyridazin-1-yl]-N-[2-[(2-ethylphenyl)amino]-2-oxidanylidene-ethyl]-N-methyl-ethanamide cid_2585250 AC1M9L9R 2-(4,5-dichloro-6-oxopyridazin-1-yl)-N-[2-(2-ethylanilino)-2-oxoethyl]-N-methylacetamide Z19024590 HMS2538G24 2-(4,5-dichloro-6-keto-pyridazin-1-yl)-N-[2-(2-ethylanilino)-2-keto-ethyl]-N-methyl-acetamide AKOS033655360 MolPort-005-531-827 [ Show all ]
Inchi Key	MRFCCGDBEJIXFA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H18Cl2N4O3/c1-3-11-6-4-5-7-13(11)21-14(24)9-22(2)15(25)10-23-17(26)16(19)12(18)8-20-23/h4-8H,3,9-10H2,1-2H3,(H,21,24)
PubChem CID	2585250
ChEMBL	CHEMBL1374788
IUPHAR	N/A
BindingDB	42061
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
212351	Galanin receptor type 2	O43603	GALR2	Homo sapiens (Human)	387
212353	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
212354	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
212352	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384

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