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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	LZ0EU1YHCK
Molecular formula	C25H28ClN3O2
IUPAC name	[6-chloro-1-[2-(dimethylamino)ethyl]indol-3-yl]-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanone
Molecular weight	437.968
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.3
Synonyms	CHEMBL3416885 RO 5028442 (6-Chloro-1-(2-(dimethylamino)ethyl)indol-3-yl)-spiro(1H-isobenzofuran-3,4'-piperidine)-1'-yl-methanone HY-12981 SCHEMBL4361592 BDBM50077217 RG 7314 CS-7944 Ro-5028442 SCHEMBL4361597 RG7713 DB12721 Ro5028442 920022-47-5 Methanone, (6-chloro-1-(2-(dimethylamino)ethyl)-1H-indol-3-yl)spiro(isobenzofuran-1(3H),4'-piperidin)-1'-yl- UNII-LZ0EU1YHCK [ Show all ]
Inchi Key	QZXVLRCMAHJVIP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H28ClN3O2/c1-27(2)13-14-29-16-21(20-8-7-19(26)15-23(20)29)24(30)28-11-9-25(10-12-28)22-6-4-3-5-18(22)17-31-25/h3-8,15-16H,9-14,17H2,1-2H3
PubChem CID	59657596
ChEMBL	CHEMBL3416885
IUPHAR	N/A
BindingDB	50077217
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
453199	Vasopressin V1a receptor	P37288	AVPR1A	Homo sapiens (Human)	418
453200	Vasopressin V1a receptor	Q62463	Avpr1a	Mus musculus (Mouse)	423

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