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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MK 0893
Molecular formula	C32H27Cl2N3O4
IUPAC name	3-[[4-[(1S)-1-[3-(3,5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]benzoyl]amino]propanoic acid
Molecular weight	588.485
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	6.8
Synonyms	3736AC beta-Alanine, N-((4-((1S)-1-(3-(3,5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl)ethyl)phenyl)carbonyl)- DTXSID40468726 MK0893 870823-12-4 KB-78873 SCHEMBL675777 3-[[4-[(1S)-1-[3-(3,5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]benzoyl]amino]propanoic acid AKOS016011529 CS-0324 MK-0893 ZINC68250425 C32H27Cl2N3O4 GTPL9135 MolPort-027-836-665 CHEMBL1933349 KS-00001DU8 UNII-CCP2U6LWTP 3-[[4-[(1~{s})-1-[3-[3,5-Bis(Chloranyl)phenyl]-5-(6-Methoxynaphthalen-2-Yl)pyrazol-1-Yl]ethyl]phenyl]carbonylamino]propanoic Acid BDBM50360601 DB12044 MK-0893-005 5MV CCP2U6LWTP HY-50663 N-[(4-{(1S)-1-[3-(3,5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl]ethyl}phenyl)carbonyl]-beta-alanine (S)-3-(4-(1-(3-(3,5-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl)ethyl)benzamido)propanoic acid A3608 compound 9m [PMID: 22708876] W-5484 [ Show all ]
Inchi Key	DNTVJEMGHBIUMW-IBGZPJMESA-N
Inchi ID	InChI=1S/C32H27Cl2N3O4/c1-19(20-3-5-21(6-4-20)32(40)35-12-11-31(38)39)37-30(18-29(36-37)25-14-26(33)17-27(34)15-25)24-8-7-23-16-28(41-2)10-9-22(23)13-24/h3-10,13-19H,11-12H2,1-2H3,(H,35,40)(H,38,39)/t19-/m0/s1
PubChem CID	11570626
ChEMBL	CHEMBL1933349
IUPHAR	9135
BindingDB	50360601
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
64644	Gastric inhibitory polypeptide receptor	P48546	GIPR	Homo sapiens (Human)	466
64645	Glucagon receptor	P47871	GCGR	Homo sapiens (Human)	477
64646	Glucagon receptor	Q61606	Gcgr	Mus musculus (Mouse)	485
64649	Glucagon receptor	P30082	Gcgr	Rattus norvegicus (Rat)	485
64648	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
553573	Pituitary adenylate cyclase-activating polypeptide type I receptor	P41586	ADCYAP1R1	Homo sapiens (Human)	468
64647	Vasoactive intestinal polypeptide receptor 1	P32241	VIPR1	Homo sapiens (Human)	457
64650	Vasoactive intestinal polypeptide receptor 2	P41587	VIPR2	Homo sapiens (Human)	438

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