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| Name | Vasoactive intestinal polypeptide receptor 2 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | VIPR2 |
| Synonym | VPAC2 VIP-R-2 VIP and PACAP receptor 2 PVR3 Pituitary adenylate cyclase-activating polypeptide type III receptor [ Show all ] |
| Disease | Unspecified Chronic obstructive pulmonary disease Hypertension |
| Length | 438 |
| Amino acid sequence | MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSRNGSEGALQFHRGSRAQSFLQTETSVI |
| UniProt | P41587 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P41587 |
| 3D structure model | This predicted structure model is from GPCR-EXP P41587. |
| BioLiP | N/A |
| Therapeutic Target Database | T06182 |
| ChEMBL | CHEMBL4532 |
| IUPHAR | 372 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 536008 |  CHEMBL3921396 | C25H34N2O5S | 474.616 | 6 / 4 | 2.6 | Yes |
| 15531 |  VIP Ala21 | C144H231N43O42S | 3268.75 | 49 / 48 | -14.8 | No |
| 19513 |  VIP Ala15 | C144H231N43O42S | 3268.75 | 49 / 48 | -14.8 | No |
| 536651 |  CHEMBL3901991 | C23H26Cl2N2O4 | 465.371 | 4 / 4 | 2.8 | Yes |
| 536653 |  CHEMBL3976408 | C27H29N3O7S | 539.603 | 8 / 4 | 2.6 | No |
| 536681 |  CHEMBL3912591 | C28H33N3O5S | 523.648 | 7 / 5 | 2.8 | No |
| 27732 |  CID 76310175 | C164H268N44O43 | 3544.21 | 51 / 52 | -9.4 | No |
| 536729 |  CHEMBL3975462 | C30H32N2O4 | 484.596 | 4 / 4 | 3.9 | Yes |
| 536747 |  CHEMBL3916426 | C25H31ClN2O4 | 458.983 | 4 / 4 | 2.3 | Yes |
| 536912 |  CHEMBL3890096 | C30H34N2O7S | 566.669 | 8 / 3 | 3.1 | No |
| 536951 |  CHEMBL3934784 | C24H31N3O7S | 505.586 | 8 / 3 | 1.9 | No |
| 537008 |  CHEMBL3942350 | C26H33BrN2O4 | 517.464 | 4 / 4 | 2.9 | No |
| 537041 |  CHEMBL3934346 | C19H23N3O6S | 421.468 | 7 / 3 | 1.7 | Yes |
| 47591 |  VIP Ala6 | C141H234N44O42S | 3249.75 | 50 / 49 | -16.6 | No |
| 51961 |  BDBM86050 | C159H258N46O47S | 3598.15 | 56 / 53 | -18.9 | No |
| 537289 |  CHEMBL3939316 | C32H41N3O5S | 579.756 | 7 / 5 | 4.6 | No |
| 537441 |  CHEMBL3898495 | C31H39N3O5S | 565.729 | 7 / 5 | 4.1 | No |
| 537458 |  CHEMBL3908152 | C29H34N2O6S | 538.659 | 7 / 5 | 2.3 | No |
| 64650 |  MK 0893 | C32H27Cl2N3O4 | 588.485 | 5 / 2 | 6.8 | No |
| 537568 |  CHEMBL3901253 | C30H37N3O5S | 551.702 | 7 / 5 | 3.6 | No |
| 67364 |  VIP Ala27 | C144H232N44O42S | 3283.77 | 50 / 49 | -16.3 | No |
| 71216 |  VIP Ala14 | C144H231N41O42S | 3240.74 | 49 / 47 | -13.8 | No |
| 74100 |  VIP Ala1 | C144H236N42O42S | 3259.78 | 49 / 48 | -14.8 | No |
| 79319 |  CID 76328238 | C160H257N45O45 | 3531.09 | 52 / 53 | -14.1 | No |
| 538018 |  CHEMBL3950576 | C31H35N3O7S | 593.695 | 8 / 4 | 2.6 | No |
| 82825 |  VIP Ala19 | C145H234N44O42S | 3297.79 | 50 / 49 | -16.0 | No |
| 538049 |  CHEMBL3929255 | C30H35N3O6S | 565.685 | 7 / 5 | 2.5 | No |
| 538051 |  CHEMBL3971282 | C22H29N3O6S | 463.549 | 7 / 3 | 2.9 | Yes |
| 538052 |  CHEMBL3927571 | C22H29N3O6S | 463.549 | 7 / 3 | 2.9 | Yes |
| 538088 |  CHEMBL3889643 | C30H34N2O6S | 550.67 | 7 / 3 | 3.0 | No |
| 86672 |  CID 76313784 | C155H248N46O46 | 3491.97 | 53 / 54 | -17.7 | No |
| 538164 |  CHEMBL3981373 | C27H29N3O7S | 539.603 | 8 / 4 | 2.6 | No |
| 91102 |  VIP Ala28 | C146H237N43O41S | 3282.82 | 49 / 48 | -13.5 | No |
| 538268 |  CHEMBL3968923 | C33H39N3O6S | 605.75 | 7 / 5 | 3.4 | No |
| 93900 |  CID 16214685 | C142H223N39O40S | 3148.64 | 48 / 48 | -12.0 | No |
| 538453 |  CHEMBL3905722 | C29H34N2O5S | 522.66 | 6 / 4 | 3.5 | No |
| 538526 |  CHEMBL3980376 | C29H34N2O7S | 554.658 | 8 / 4 | 2.8 | No |
| 538533 |  CHEMBL3899196 | C28H31N3O6 | 505.571 | 6 / 4 | 0.7 | No |
| 106350 |  BDBM50445120 | C160H257N45O45 | 3531.09 | 52 / 51 | -14.9 | No |
| 109582 |  BDBM86051 | C144H244N44O38 | 3199.81 | 46 / 47 | -11.8 | No |
| 538864 |  CHEMBL3946718 | C25H33N3O6S | 503.614 | 7 / 3 | 4.0 | No |
| 538865 |  CHEMBL3949395 | C25H33N3O6S | 503.614 | 7 / 3 | 4.0 | No |
| 538885 |  CHEMBL3912978 | C33H37N3O8S | 635.732 | 9 / 3 | 3.1 | No |
| 539016 |  CHEMBL3947162 | C26H28ClN3O6S | 546.035 | 7 / 3 | 4.3 | No |
| 539017 |  CHEMBL3937601 | C26H28ClN3O6S | 546.035 | 7 / 3 | 4.3 | No |
| 539041 |  CHEMBL3986723 | C28H32N2O7S2 | 572.691 | 8 / 4 | 2.0 | No |
| 525160 |  CID 44139848 | C148H228N40O39S | 3223.75 | 47 / 48 | -8.7 | No |
| 128916 |  BDBM50200210 | C174H280N52O49S | 3916.53 | 59 / 59 | -18.8 | No |
| 539262 |  CHEMBL3906479 | C25H30N2O4 | 422.525 | 4 / 4 | 1.9 | Yes |
| 539303 |  CHEMBL3942309 | C23H30N4O6S | 490.575 | 8 / 3 | 2.8 | Yes |
| 539304 |  CHEMBL3945004 | C23H30N4O6S | 490.575 | 8 / 3 | 2.8 | Yes |
| 539493 |  CHEMBL3935754 | C25H27N3O6S | 497.566 | 7 / 3 | 3.2 | Yes |
| 539494 |  CHEMBL3933055 | C25H27N3O6S | 497.566 | 7 / 3 | 3.2 | Yes |
| 138684 |  PHA-543613 | C15H17N3O2 | 271.32 | 4 / 1 | 1.5 | Yes |
| 145208 |  VIP Ala8 | C146H238N44O40S | 3281.84 | 48 / 48 | -11.8 | No |
| 539694 |  CHEMBL3919710 | C29H31ClN2O4 | 507.027 | 4 / 4 | 3.5 | No |
| 153211 |  BDBM50445115 | C163H263N45O44 | 3557.17 | 51 / 50 | -12.5 | No |
| 539956 |  CHEMBL3936562 | C29H33N3O6S | 551.658 | 7 / 5 | 2.0 | No |
| 540206 |  CHEMBL3977945 | C28H29N3O6 | 503.555 | 6 / 4 | 3.0 | No |
| 540246 |  CHEMBL3929924 | C27H29FN2O5S | 512.596 | 7 / 4 | 2.9 | No |
| 540275 |  CHEMBL3895360 | C32H32N2O4 | 508.618 | 4 / 4 | 4.4 | No |
| 167782 |  VIP Ala20 | C144H231N43O42S | 3268.75 | 49 / 48 | -14.8 | No |
| 540339 |  CHEMBL3911013 | C31H38N2O5S | 550.714 | 6 / 4 | 4.5 | No |
| 554143 |  Secrepan | C130H219N43O42 | 3056.44 | 48 / 52 | -13.4 | No |
| 540430 |  CHEMBL3923227 | C22H27N3O7S | 477.532 | 8 / 2 | 1.5 | Yes |
| 540431 |  CHEMBL3926006 | C22H27N3O7S | 477.532 | 8 / 2 | 1.5 | Yes |
| 173273 |  BDBM85078 | C65H111N15O13 | 1310.69 | 15 / 15 | 3.4 | No |
| 540502 |  CHEMBL3951458 | C29H31ClN2O4 | 507.027 | 4 / 4 | 3.7 | No |
| 540507 |  CHEMBL3980013 | C30H36N2O6S | 552.686 | 7 / 4 | 3.7 | No |
| 540604 |  CHEMBL3924879 | C29H35N3O5S | 537.675 | 7 / 4 | 2.9 | No |
| 540611 |  CHEMBL3949853 | C20H25N3O6S | 435.495 | 7 / 3 | 2.1 | Yes |
| 540612 |  CHEMBL3980522 | C20H25N3O6S | 435.495 | 7 / 3 | 2.1 | Yes |
| 184975 |  VIP Ala3 | C146H238N44O40S | 3281.84 | 48 / 48 | -11.8 | No |
| 186467 |  VIP Ala2 | C147H240N44O40S | 3295.86 | 48 / 48 | -11.4 | No |
| 540779 |  CHEMBL3982346 | C28H30N2O7S | 538.615 | 8 / 4 | 2.6 | No |
| 188033 |  VIP Ala12 | C144H231N41O42S | 3240.74 | 49 / 47 | -13.8 | No |
| 541022 |  CHEMBL3927669 | C28H31ClN2O5S | 543.075 | 6 / 3 | 4.0 | No |
| 541107 |  CHEMBL3927475 | C29H32N2O7S | 552.642 | 8 / 4 | 2.5 | No |
| 541120 |  CHEMBL3953824 | C29H33ClN2O5S | 557.102 | 6 / 4 | 4.2 | No |
| 201424 |  VIP Ala13 | C144H232N44O42S | 3283.77 | 50 / 49 | -16.3 | No |
| 202780 |  VIP Ala9 | C146H237N43O41S | 3282.82 | 49 / 48 | -13.5 | No |
| 541313 |  CHEMBL3923946 | C27H29N3O4 | 459.546 | 5 / 4 | 2.1 | Yes |
| 541333 |  CHEMBL3934063 | C29H33N3O7S | 567.657 | 8 / 2 | 3.4 | No |
| 206372 |  CID 76310087 | C155H250N46O47 | 3509.98 | 55 / 55 | -20.4 | No |
| 212775 |  VIP Ala10 | C141H234N44O41S | 3233.75 | 49 / 48 | -16.2 | No |
| 541762 |  CHEMBL3932021 | C31H37N3O6S | 579.712 | 7 / 5 | 3.0 | No |
| 541899 |  CHEMBL3896204 | C21H26N2O3 | 354.45 | 4 / 4 | 1.2 | Yes |
| 542070 |  CHEMBL3952350 | C27H29N3O4 | 459.546 | 5 / 4 | 2.4 | Yes |
| 542235 |  CHEMBL3936135 | C28H29BrN2O4 | 537.454 | 4 / 4 | 3.8 | No |
| 542342 |  CHEMBL3941270 | C29H34N2O5S | 522.66 | 6 / 4 | 3.5 | No |
| 542454 |  CHEMBL3913678 | C23H27ClN2O4 | 430.929 | 4 / 4 | 2.1 | Yes |
| 542466 |  CHEMBL3938565 | C29H34N2O5S | 522.66 | 6 / 4 | 3.6 | No |
| 542479 |  CHEMBL3982321 | C28H29N3O6 | 503.555 | 6 / 4 | 3.0 | No |
| 542599 |  CHEMBL3939693 | C27H32N2O4 | 448.563 | 4 / 4 | 2.3 | Yes |
| 542894 |  CHEMBL3922176 | C30H37N3O5S | 551.702 | 7 / 5 | 3.7 | No |
| 529040 |  CHEMBL3736134 | C150H227FN40O39S | 3265.76 | 48 / 48 | -8.2 | No |
| 542965 |  CHEMBL3918682 | C22H28N2O5S | 432.535 | 6 / 4 | 1.3 | Yes |
| 263502 |  CHEMBL2159347 | C32H27Cl2N3O4 | 588.485 | 5 / 2 | 6.8 | No |
| 264258 |  VIP Ala17 | C145H234N44O42 | 3265.73 | 49 / 49 | -15.6 | No |
| 543177 |  CHEMBL3963769 | C27H29N3O4 | 459.546 | 5 / 4 | 2.1 | Yes |
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