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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	N-arachidonyl glycine receptor
Species	Homo sapiens (Human)
Gene	GPR18
Synonym	GPCRW G-protein coupled receptor 18 N-arachidonoyol glycine receptor NAGly receptor GPR18
Disease	N/A
Length	331
Amino acid sequence	MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVMLYRNYLRSMRRKSFRSGSLRSLSNINSEML
UniProt	Q14330
Protein Data Bank	N/A
GPCR-HGmod model	Q14330
3D structure model	This predicted structure model is from GPCR-EXP Q14330.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2384898
IUPHAR	89
DrugBank	BE0002304

Ligand

Name	CHEMBL2181543
Molecular formula	C27H32O4
IUPAC name	7-(1-butylcyclopentyl)-5-methoxy-3-[(2-methoxyphenyl)methyl]chromen-2-one
Molecular weight	420.549
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	7.9
Synonyms	BDBM50398217
Inchi Key	JDYPQQKFCAAXRZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H32O4/c1-4-5-12-27(13-8-9-14-27)21-17-24(30-3)22-16-20(26(28)31-25(22)18-21)15-19-10-6-7-11-23(19)29-2/h6-7,10-11,16-18H,4-5,8-9,12-15H2,1-3H3
PubChem CID	70678102
ChEMBL	CHEMBL2181543
IUPHAR	N/A
BindingDB	50398217
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Activity	25.0 %	PMID23679955	ChEMBL
IC50	<10000.0 nM	PMID23679955	BindingDB,ChEMBL

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