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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
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GPCR

Name	D(1A) dopamine receptor
Species	Sus scrofa (Pig)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	P50130
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5067
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL2207643
Molecular formula	C22H24N2O
IUPAC name	1-(azulen-1-ylmethyl)-4-(2-methoxyphenyl)piperazine
Molecular weight	332.447
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.3
Synonyms	1-[4-(azulenylmethyl)piperazinyl]-2-methoxybenzene fauc-3019 AC1MVZR6 SBB056630 1-(1-azulenylmethyl)-4-(2-methoxyphenyl)piperazine 387360-48-7 KB-272557 AKOS024327376 ST50451974 1-(azulen-1-ylmethyl)-4-(2-methoxyphenyl)piperazine MCULE-8261633067 BDBM50401953 ZINC54960009 [ Show all ]
Inchi Key	MNVDCQLMHFFYCU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24N2O/c1-25-22-10-6-5-9-21(22)24-15-13-23(14-16-24)17-19-12-11-18-7-3-2-4-8-20(18)19/h2-12H,13-17H2,1H3
PubChem CID	3716121
ChEMBL	CHEMBL2207643
IUPHAR	N/A
BindingDB	50401953
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	500.0 nM	PMID23099096	BindingDB,ChEMBL

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