You can:
Name | G-protein coupled receptor 55 |
---|---|
Species | Homo sapiens (Human) |
Gene | GPR55 |
Synonym | GPR55 |
Disease | N/A |
Length | 319 |
Amino acid sequence | MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG |
UniProt | Q9Y2T6 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9Y2T6 |
3D structure model | This predicted structure model is from GPCR-EXP Q9Y2T6. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1075322 |
IUPHAR | 109 |
DrugBank | BE0005802 |
Name | CHEMBL3221184 |
---|---|
Molecular formula | C16H18N2OS |
IUPAC name | (2Z)-2-[(4-propan-2-ylphenyl)methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-one |
Molecular weight | 286.393 |
Hydrogen bond acceptor | 3 |
Hydrogen bond donor | 0 |
XlogP | 3.7 |
Synonyms | N/A |
Inchi Key | ONQXDSAOZGJTQF-UVTDQMKNSA-N |
Inchi ID | InChI=1S/C16H18N2OS/c1-11(2)13-6-4-12(5-7-13)10-14-15(19)18-8-3-9-20-16(18)17-14/h4-7,10-11H,3,8-9H2,1-2H3/b14-10- |
PubChem CID | 10902223 |
ChEMBL | CHEMBL3221184 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Activity | 13.0 % | MedChemComm, (2014) 5:5:632 | ChEMBL |
IC50 | <10000.0 nM | MedChemComm, (2014) 5:5:632 | ChEMBL |
Inhibition | 38.0 % | MedChemComm, (2014) 5:5:632 | ChEMBL |
zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218