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Name | G-protein coupled receptor 55 |
---|---|
Species | Homo sapiens (Human) |
Gene | GPR55 |
Synonym | GPR55 |
Disease | N/A |
Length | 319 |
Amino acid sequence | MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG |
UniProt | Q9Y2T6 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9Y2T6 |
3D structure model | This predicted structure model is from GPCR-EXP Q9Y2T6. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1075322 |
IUPHAR | 109 |
DrugBank | BE0005802 |
Name | CHEMBL2177263 |
---|---|
Molecular formula | C26H32O3 |
IUPAC name | 3-benzyl-5-methoxy-7-(2-methyloctan-2-yl)chromen-2-one |
Molecular weight | 392.539 |
Hydrogen bond acceptor | 3 |
Hydrogen bond donor | 0 |
XlogP | 8.2 |
Synonyms | BDBM50398223 |
Inchi Key | XGVMJRRAQJNWAN-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C26H32O3/c1-5-6-7-11-14-26(2,3)21-17-23(28-4)22-16-20(25(27)29-24(22)18-21)15-19-12-9-8-10-13-19/h8-10,12-13,16-18H,5-7,11,14-15H2,1-4H3 |
PubChem CID | 70677959 |
ChEMBL | CHEMBL2177263 |
IUPHAR | N/A |
BindingDB | 50398223 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Activity | 51.0 % | PMID23679955 | ChEMBL |
IC50 | 10000.0 nM | PMID23679955 | BindingDB,ChEMBL |
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