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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 1B
Species	Canis lupus familiaris (Dog)
Gene	HTR1B
Synonym	5-HT-1B 5-HT1B 5-HT1D subtype beta 5-HTR1B Serotonin receptor 1B
Disease	N/A for non-human GPCRs
Length	389
Amino acid sequence	MEAAGAPCAPPPPAGSQTGAPPANLSSAPHNCSAEGYIYQDSVALPWKVLLVILLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDLWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSDCVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSVNSRAPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCAG
UniProt	P79250
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	A-85380
Molecular formula	C9H12N2O
IUPAC name	3-[[(2S)-azetidin-2-yl]methoxy]pyridine
Molecular weight	164.208
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	0.6
Synonyms	CHEMBL59986 161416-98-4 NCGC00387223-01 3-[(2S)-azetidin-2-ylmethoxy]pyridine AKOS030230435 SCHEMBL676026 A 85380 D0Y6OE 3-((S)-1-Azetidin-2-ylmethoxy)-pyridine A85380 Pyridine, 3-(2-azetidinylmethoxy)-, (S)- 3-[[(2S)-azetidin-2-yl]methoxy]pyridine BDBM50049750 ZINC3805142 (S)-3-(AZETIDIN-2-YLMETHOXY)PYRIDINE A-159470 GTPL5460 3-(2(s)-azetidinylmethoxy)pyridine AC1NSJQT Pyridine, 3-[(2S)-2-azetidinylmethoxy]- [ Show all ]
Inchi Key	XKFMBGWHHBCWCD-QMMMGPOBSA-N
Inchi ID	InChI=1S/C9H12N2O/c1-2-9(6-10-4-1)12-7-8-3-5-11-8/h1-2,4,6,8,11H,3,5,7H2/t8-/m0/s1
PubChem CID	5310969
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50049750
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	PMID8887981	BindingDB

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