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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Olfactory receptor 5K1
Species	Homo sapiens (Human)
Gene	OR5K1
Synonym	HTPCRX10 Olfactory receptor OR3-8
Disease	N/A
Length	308
Amino acid sequence	MAEENHTMKNEFILTGFTDHPELKTLLFVVFFAIYLITVVGNISLVALIFTHRRLHTPMYIFLGNLALVDSCCACAITPKMLENFFSENKRISLYECAVQFYFLCTVETADCFLLAAMAYDRYVAICNPLQYHIMMSKKLCIQMTTGAFIAGNLHSMIHVGLVFRLVFCGSNHINHFYCDILPLYRLSCVDPYINELVLFIFSGSVQVFTIGSVLISYLYILLTIFKMKSKEGRAKAFSTCASHFLSVSLFYGSLFFMYVRPNLLEEGDKDIPAAILFTIVVPLLNPFIYSLRNREVISVLRKILMKK
UniProt	Q8NHB7
Protein Data Bank	N/A
GPCR-HGmod model	Q8NHB7
3D structure model	This predicted structure model is from GPCR-EXP Q8NHB7.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3721312
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	2-t-Butylcyclohexyloxy-2-butanol
Molecular formula	C14H28O2
IUPAC name	1-(2-tert-butylcyclohexyl)oxybutan-2-ol
Molecular weight	228.376
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.8
Synonyms	1-((2-tert-Butylcyclohexyl)oxy)butan-2-ol A810537 SCHEMBL118256 1-(2-tert-butylcyclohexyl)oxybutan-2-ol AKOS028114617 2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]- EC 412-300-2 1-(2-t-butylcyclohexyloxy)-2-butanol AC1L4URD 1-(2-tert-butylcyclohexyloxy)-2-butanol GQBVHGLNSHPKPG-UHFFFAOYSA-N 1-(2-tert-butylcyclohexyl)oxy-2-butanol AC1Q58H8 2-Butanol, 1-((2-(1,1-dimethylethyl)cyclohexyl)oxy)- CHEMBL3733013 [ Show all ]
Inchi Key	GQBVHGLNSHPKPG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H28O2/c1-5-11(15)10-16-13-9-7-6-8-12(13)14(2,3)4/h11-13,15H,5-10H2,1-4H3
PubChem CID	164422
ChEMBL	CHEMBL3733013
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	75.0 %	None	ChEMBL

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