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GPCR

NameOlfactory receptor 5K1
SpeciesHomo sapiens (Human)
GeneOR5K1
SynonymHTPCRX10
Olfactory receptor OR3-8
DiseaseN/A
Length308
Amino acid sequenceMAEENHTMKNEFILTGFTDHPELKTLLFVVFFAIYLITVVGNISLVALIFTHRRLHTPMYIFLGNLALVDSCCACAITPKMLENFFSENKRISLYECAVQFYFLCTVETADCFLLAAMAYDRYVAICNPLQYHIMMSKKLCIQMTTGAFIAGNLHSMIHVGLVFRLVFCGSNHINHFYCDILPLYRLSCVDPYINELVLFIFSGSVQVFTIGSVLISYLYILLTIFKMKSKEGRAKAFSTCASHFLSVSLFYGSLFFMYVRPNLLEEGDKDIPAAILFTIVVPLLNPFIYSLRNREVISVLRKILMKK
UniProtQ8NHB7
Protein Data BankN/A
GPCR-HGmod modelQ8NHB7
3D structure modelThis predicted structure model is from GPCR-EXP Q8NHB7.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3721312
IUPHARN/A
DrugBankN/A

Ligand

Name28219-60-5
Molecular formulaC13H22O
IUPAC name(E)-2-methyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol
Molecular weight194.318
Hydrogen bond acceptor1
Hydrogen bond donor1
XlogP3.1
Synonyms2-Buten-1-ol, 2-methyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-
2-Methyl-4-(2,2,3-trimethyl-3-cyclopentenyl)-2-butene-1-ol
KB-173675
(e)-2-methyl-4-(2,2,3-trimethylcyclopent-3-enyl)but-2-en-1-ol
AC1O5P7Y
[ Show all ]
Inchi KeyMTVBNJVZZAQKRV-BJMVGYQFSA-N
Inchi IDInChI=1S/C13H22O/c1-10(9-14)5-7-12-8-6-11(2)13(12,3)4/h5-6,12,14H,7-9H2,1-4H3/b10-5+
PubChem CID6438195
ChEMBLCHEMBL3729392
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
Inhibition50.0 %NoneChEMBL

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