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GPCR

NameOlfactory receptor 5K1
SpeciesHomo sapiens (Human)
GeneOR5K1
SynonymHTPCRX10
Olfactory receptor OR3-8
DiseaseN/A
Length308
Amino acid sequenceMAEENHTMKNEFILTGFTDHPELKTLLFVVFFAIYLITVVGNISLVALIFTHRRLHTPMYIFLGNLALVDSCCACAITPKMLENFFSENKRISLYECAVQFYFLCTVETADCFLLAAMAYDRYVAICNPLQYHIMMSKKLCIQMTTGAFIAGNLHSMIHVGLVFRLVFCGSNHINHFYCDILPLYRLSCVDPYINELVLFIFSGSVQVFTIGSVLISYLYILLTIFKMKSKEGRAKAFSTCASHFLSVSLFYGSLFFMYVRPNLLEEGDKDIPAAILFTIVVPLLNPFIYSLRNREVISVLRKILMKK
UniProtQ8NHB7
Protein Data BankN/A
GPCR-HGmod modelQ8NHB7
3D structure modelThis predicted structure model is from GPCR-EXP Q8NHB7.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3721312
IUPHARN/A
DrugBankN/A

Ligand

Namel-Menthol
Molecular formulaC10H20O
IUPAC name(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-ol
Molecular weight156.269
Hydrogen bond acceptor1
Hydrogen bond donor1
XlogP3.0
SynonymsDivK1c_000820
NCGC00164247-03
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
DSSTox_RID_76516
NOOLISFMXDJSKH-KXUCPTDWBX
[ Show all ]
Inchi KeyNOOLISFMXDJSKH-KXUCPTDWSA-N
Inchi IDInChI=1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m1/s1
PubChem CID16666
ChEMBLCHEMBL470670
IUPHARN/A
BindingDBN/A
DrugBankDB00825

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
Inhibition50.0 %NoneChEMBL

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