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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Type-1A angiotensin II receptor
Species	Rattus norvegicus (Rat)
Gene	Agtr1
Synonym	Angiotensin II type-1A receptor AT1A
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSSAKKPASCFEVE
UniProt	P25095
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL329
IUPHAR	34
DrugBank	N/A

Ligand

Name	CHEMBL517230
Molecular formula	C27H29N3O4S
IUPAC name	2-[4-[[2-butyl-5-(ethylsulfamoyl)benzimidazol-1-yl]methyl]phenyl]benzoic acid
Molecular weight	491.606
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	5.2
Synonyms	BDBM50412547
Inchi Key	CXVYUQFMHJTBDM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H29N3O4S/c1-3-5-10-26-29-24-17-21(35(33,34)28-4-2)15-16-25(24)30(26)18-19-11-13-20(14-12-19)22-8-6-7-9-23(22)27(31)32/h6-9,11-17,28H,3-5,10,18H2,1-2H3,(H,31,32)
PubChem CID	44570216
ChEMBL	CHEMBL517230
IUPHAR	N/A
BindingDB	50412547
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Kd	79.43 nM	PMID19013821	BindingDB,ChEMBL
pA10	6.2 -	PMID19013821	ChEMBL

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