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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Taste receptor type 1 member 2
Species	Homo sapiens (Human)
Gene	TAS1R2
Synonym	taste receptor, type 1, member 2 taste receptor TAS1R2 T1R2 Sweet taste receptor T1R2 GPR71 G-protein coupled receptor 71 G protein-coupled receptor 71 TR2 [ Show all ]
Disease	N/A
Length	839
Amino acid sequence	MGPRAKTISSLFFLLWVLAEPAENSDFYLPGDYLLGGLFSLHANMKGIVHLNFLQVPMCKEYEVKVIGYNLMQAMRFAVEEINNDSSLLPGVLLGYEIVDVCYISNNVQPVLYFLAHEDNLLPIQEDYSNYISRVVAVIGPDNSESVMTVANFLSLFLLPQITYSAISDELRDKVRFPALLRTTPSADHHIEAMVQLMLHFRWNWIIVLVSSDTYGRDNGQLLGERVARRDICIAFQETLPTLQPNQNMTSEERQRLVTIVDKLQQSTARVVVVFSPDLTLYHFFNEVLRQNFTGAVWIASESWAIDPVLHNLTELRHLGTFLGITIQSVPIPGFSEFREWGPQAGPPPLSRTSQSYTCNQECDNCLNATLSFNTILRLSGERVVYSVYSAVYAVAHALHSLLGCDKSTCTKRVVYPWQLLEEIWKVNFTLLDHQIFFDPQGDVALHLEIVQWQWDRSQNPFQSVASYYPLQRQLKNIQDISWHTINNTIPMSMCSKRCQSGQKKKPVGIHVCCFECIDCLPGTFLNHTEDEYECQACPNNEWSYQSETSCFKRQLVFLEWHEAPTIAVALLAALGFLSTLAILVIFWRHFQTPIVRSAGGPMCFLMLTLLLVAYMVVPVYVGPPKVSTCLCRQALFPLCFTICISCIAVRSFQIVCAFKMASRFPRAYSYWVRYQGPYVSMAFITVLKMVIVVIGMLATGLSPTTRTDPDDPKITIVSCNPNYRNSLLFNTSLDLLLSVVGFSFAYMGKELPTNYNEAKFITLSMTFYFTSSVSLCTFMSAYSGVLVTIVDLLVTVLNLLAISLGYFGPKCYMILFYPERNTPAYFNSMIQGYTMRRD
UniProt	Q8TE23
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	N/A
DrugBank	BE0000395

Ligand

Name	sucrose
Molecular formula	C12H22O11
IUPAC name	(2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
Molecular weight	342.297
Hydrogen bond acceptor	11
Hydrogen bond donor	8
XlogP	-3.7
Synonyms	SR-01000883983-1 Sucrose ACS grade Sucrose, analytical standard, for enzymatic assay kit SCA20 Sucrose, dust Sucrose, Low Endotoxin, PharmaGrade, USP/NF, Ph Eur, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production. Sucrose, reagent grade Sugar spheres (NF) UNII-C151H8M554 HSDB 500 alpha-D-fructofuranosyl alpha-L-gulopyranoside MolPort-003-926-939 alpha-D-Glucopyranosylbeta-D-fructofuranoside Polysucrose beta-D-fructofuranose-(2-1)-alpha-D-glucopyranoside bmse000804 1-alpha-D-glucopyranosyl-2-beta-D-fructofranoside CAS-57-50-1 131932-12-2 CRB0000841 2-{[3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol D(+)-Sucrose, ACS reagent 50857-68-6 DB02772 76056-38-7 FICOLL 87430-66-8 saccharose Sucraloxum Sucrose [USAN:JAN] Sucrose, BioReagent, suitable for cell culture, suitable for insect cell culture, >=99.5% (GC) Sucrose, for microbiology, ACS reagent, >=99.0% Sucrose, NIST(R) SRM(R) 17f, optical rotation Sucrose, USP Sugar,(S) White sugar a-D-Glucopyranosyl A-D-fructofuranoside KB-303246 alpha-D-Glucopyranoside, beta-D-fructofuranosyl NCGC00164248-03 b -D-Fructofuranosyl a-D-glucopyranoside S0111 beta-D-Fructofuranosyl-alpha-D-glucopyranoside (2R,3R,4S,5S,6R)-2-((2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)tetrahydrofuran-2-yloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol C00089 104242-10-6 CHEBI:17992 1481578-88-4 D(+)-OaIC 29764-06-5 D-Saccharose 5903AE DSSTox_GSID_21288 80165-03-3 Glc(alpha1->2beta)Fru ZINC4217475 SC-81182 Sucrose (JP17/NF) Sucrose, ACS reagent Sucrose, British Pharmacopoeia (BP) Reference Standard Sucrose, Grade II, plant cell culture tested Sucrose, purified Sucrose\|?-D-Fructofuranosyl ?-D-glucopyranoside Tox21_201397 Granulated sugar AKOS024306988 MFCD00006626 alpha-D-Glucopyranosyl beta-D-fructofuranoside NCI-C56597 bet a-D-fructofuranosyl-alpha-D-Glucopyranoside BIS3391 (2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol Cane sugar 12040-73-2 Compressible sugar, United States Pharmacopeia (USP) Reference Standard 1af6 D(+)-Sucrose, 99+%, for biochemistry, DNAse, RNAse and protease free 47185-09-1 D08TCV 65545-99-5 EINECS 200-334-9 85456-51-5 ST50308554 Sucrose Biochemical grade Sucrose, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent Sucrose, European Pharmacopoeia (EP) Reference Standard Sucrose, LR Sucrose, SAJ first grade Sugar, compressible (NF) UNII-YUH1C99228 component CZMRCDWAGMRECN-UGDNZRGBSA-N 880257-62-5 HY-B1779 alpha-D-Glc-(1-->2)-beta-D-Fru NCGC00164248-01 Amerfand Rock candy beta-D-Fructofuranosyl alpha-D-glucopyranoside (+)-Sucrose bmse000918 1-alpha-D-glucopyranosyl-2-beta-D-fructofuranoside CC-34575 146054-35-5 CS-0013810 220376-22-7 D-(+)-Saccharose 51909-69-4 degrees xIC 78654-77-0 Fructofuranoside, alpha-D-glucopyranosyl, beta-D WURCS=2.0/2,2,1/[ha122h-2b_2-5][a2122h-1a_1-5]/1-2/a2-b1 Saccharum Sucraloxum [INN-Latin] Sucrose, >=99.5% Sucrose, BioUltra, for molecular biology, >=99.5% (HPLC) Sucrose, for molecular biology, >=99.5% (GC) Sucrose, p.a., ACS reagent Sucrose, Vetec(TM) reagent grade, 99% Table sugar AC1L1LK0 LS-229 alpha-D-Glucopyranoside, beta-D-fructofuranosyl, homopolymer NCGC00254237-01 BDBM50108105 beta-D-Fruf-(2<->1)-alpha-D-Glcp (2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol C12H22O11 1159795-78-4 CHEBI:65313 151756-02-4 D(+)-Saccharose 30027-72-6 D-Sucrose 635681-90-2 DSSTox_RID_76060 8027-47-2 GLC-(1-2)FRU ZX-AFC000756 SR-01000883983 Sucrose (TN) Sucrose, analytical standard Sucrose, cell culture tested Sucrose, JIS special grade Sucrose, puriss., meets analytical specification of Ph. Eur., BP, NF sugar Tox21_300410 GTPL5411 alpha-(1R,2R,3S,4S,5R)-glucopyranosyl-beta-(2S,3S,4S,5R)-fructofuranoside Microse alpha-D-glucopyranosyl-(1->2)-beta-D-fructofuranoside NSC 406942 beta-(2S,3S,4S,5R)-fructofuranosyl-alpha-(1R,2R,3S,4S,5R)-glucopyranoside bmse000119 (alpha-D-Glucosido)-beta-D-fructofuranoside Carbon isotopes in sucrose, NIST(R) RM 8542, IAEA-CH-6 sucrose 1206156-82-2 Confectioner's sugar 2-[(2S,3S,4S,5R)-2,5-bis(hydroxymethyl)-3,4-dihydroxyoxolan-2-yloxy](4S,5S,2R, 3R,6R)-6-(hydroxymethyl)-2H-3,4,5,6-tetrahydropyran-3,4,5-triol D(+)-Sucrose, 99.7%, for biochemistry 47257-91-0 75398-84-4 Epitope ID:153236 86101-30-6 sacarosa Sucralox Sucrose [JAN:NF] Sucrose, AR Sucrose, for electrophoresis, >99% Sucrose, meets USP testing specifications Sucrose, United States Pharmacopeia (USP) Reference Standard Sugar, confectioner's (NF) White soft sugar (JP17) 92004-84-7 J-519846 alpha-D-Glc-(1-2)-beta-D-Fru NCGC00164248-02 Amerfond Rohrzucker beta-D-fructofuranosyl-(2↔1)-alpha-D-glucopyranoside (2R,3R,4S,5S,6R)-2-((2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)tetrahydrofuran-2-ylhydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol C-30736 100405-08-1 CCRIS 2120 146187-04-4 CZMRCDWAGMRECN-UGDNZRGBSA-N 25702-74-3 D-(+)-Sucrose 57-50-1 DSSTox_CID_1288 786702-63-4 FT-0621912 Z1601554751 Sacharose Sucrose, >=99.5% (GC) Sucrose, BioXtra, >=99.5% (GC) Sucrose, Grade I, plant cell culture tested Sucrose, pure Sucrose, Vetec(TM) reagent grade, RNase and DNase free Tox21_112093 Glucopyranoside, beta-D-fructofuranosyl, alpha-D AI3-09085 MCULE-5933491732 alpha-D-Glucopyranoside, beta-D-fructofuranosyl- NCGC00258948-01 Beet sugar BIA1125 (2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)tetrahydrofuran-2-yl]oxy-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol C151H8M554 1192061-43-0 CHEMBL253582 1566560-95-9 D(+)-Sucrose 47167-52-2 D00025 64533-66-0 DTXSID2021288 8030-20-4 [ Show all ]
Inchi Key	CZMRCDWAGMRECN-UGDNZRGBSA-N
Inchi ID	InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1
PubChem CID	5988
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	DB02772
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor.

Experimental Data

Parameter	Value	Reference	Database source
	N/A	N/A	DrugBank

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