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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	G-protein coupled receptor 55
Species	Homo sapiens (Human)
Gene	GPR55
Synonym	GPR55
Disease	N/A
Length	319
Amino acid sequence	MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
UniProt	Q9Y2T6
Protein Data Bank	N/A
GPCR-HGmod model	Q9Y2T6
3D structure model	This predicted structure model is from GPCR-EXP Q9Y2T6.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075322
IUPHAR	109
DrugBank	BE0005802

Ligand

Name	CHEMBL2181541
Molecular formula	C28H36O4
IUPAC name	5-methoxy-3-[(2-methoxyphenyl)methyl]-7-(2-methylnonan-2-yl)chromen-2-one
Molecular weight	436.592
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	8.7
Synonyms	BDBM50398219
Inchi Key	GLBHDBKJJWTLPC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H36O4/c1-6-7-8-9-12-15-28(2,3)22-18-25(31-5)23-17-21(27(29)32-26(23)19-22)16-20-13-10-11-14-24(20)30-4/h10-11,13-14,17-19H,6-9,12,15-16H2,1-5H3
PubChem CID	70678100
ChEMBL	CHEMBL2181541
IUPHAR	N/A
BindingDB	50398219
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Activity	31.0 %	PMID23679955	ChEMBL
IC50	<10000.0 nM	PMID23679955	BindingDB,ChEMBL

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