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| Name | Adenosine receptor A1 |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Adora1 |
| Synonym | A1 receptor A1-AR A1R adenosine receptor A1 RDC7 |
| Disease | N/A for non-human GPCRs |
| Length | 326 |
| Amino acid sequence | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED |
| UniProt | P25099 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL318 |
| IUPHAR | 18 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 521444 |  CHEMBL3735468 | C15H12ClN3O | 285.731 | 4 / 1 | 3.3 | Yes |
| 353 |  CHEMBL38811 | C15H15N3O2 | 269.304 | 2 / 0 | 1.5 | Yes |
| 479 |  CHEMBL38304 | C28H32N6O4 | 516.602 | 6 / 2 | 3.2 | No |
| 535 |  CHEMBL338501 | C21H14Cl2N4 | 393.271 | 3 / 1 | 5.0 | Yes |
| 609 |  CHEMBL17202 | C28H29N5O4 | 499.571 | 5 / 2 | 5.5 | No |
| 612 |  CID 53633248 | C28H29N5O4 | 499.571 | 5 / 2 | 5.5 | No |
| 654 |  CHEMBL323403 | C24H23NO3S | 405.512 | 5 / 0 | 5.9 | No |
| 735 |  CHEMBL315101 | C13H17N5 | 243.314 | 4 / 2 | 3.1 | Yes |
| 521467 |  CHEMBL3827623 | C26H36N6O3 | 480.613 | 6 / 0 | 3.9 | Yes |
| 821 |  CHEMBL72117 | C15H18N4O2 | 286.335 | 3 / 1 | 2.2 | Yes |
| 898 |  CHEMBL72007 | C19H20N4O | 320.396 | 3 / 2 | 4.1 | Yes |
| 1143 |  CHEMBL307307 | C14H15N5 | 253.309 | 4 / 0 | 2.9 | Yes |
| 1174 |  CHEMBL319971 | C17H14ClN5O2 | 355.782 | 5 / 1 | 3.2 | Yes |
| 1271 |  CHEMBL420368 | C14H11ClF5N5 | 379.719 | 9 / 1 | 4.9 | Yes |
| 1318 |  CHEMBL319356 | C9H12N4 | 176.223 | 3 / 2 | 1.5 | Yes |
| 1334 |  MRS-1042 | C24H28O5 | 396.483 | 5 / 0 | 6.0 | No |
| 1420 |  8-Phenylxanthine | C11H8N4O2 | 228.211 | 3 / 3 | 0.9 | Yes |
| 1501 |  CHEMBL610601 | C30H31N7O6 | 585.621 | 9 / 5 | 2.3 | No |
| 1816 |  CHEMBL603861 | C21H20F2N4O4 | 430.412 | 7 / 0 | 2.2 | Yes |
| 1930 |  2-(3-Cyclopentyl-1-propynyl)adenosine | C18H23N5O4 | 373.413 | 8 / 4 | 1.8 | Yes |
| 2179 |  CHEMBL343527 | C18H14N4O4 | 350.334 | 5 / 1 | 1.8 | Yes |
| 2961 |  CHEMBL367705 | C13H13N5O | 255.281 | 4 / 2 | 0.7 | Yes |
| 3109 |  CHEMBL607881 | C15H20IN5O4 | 461.26 | 8 / 4 | 1.6 | Yes |
| 3183 |  CHEMBL72953 | C14H15F2N5 | 291.306 | 6 / 1 | 3.7 | Yes |
| 3323 |  CHEMBL3093226 | C21H27N5O3 | 397.479 | 5 / 0 | 2.7 | Yes |
| 3434 |  CHEMBL2113345 | C17H18N4O4 | 342.355 | 5 / 3 | 1.8 | Yes |
| 3611 |  CHEMBL325664 | C19H23N5O | 337.427 | 5 / 1 | 3.5 | Yes |
| 3860 |  316173-57-6 | C20H19N7O2 | 389.419 | 7 / 1 | 2.7 | Yes |
| 4139 |  CHEMBL603991 | C19H24N6O4 | 400.439 | 9 / 5 | 1.7 | Yes |
| 4269 |  BDBM50052395 | C14H21NO5 | 283.324 | 6 / 0 | 0.8 | Yes |
| 4487 |  CHEMBL610386 | C13H19N5O5 | 325.325 | 9 / 5 | -0.2 | Yes |
| 4518 |  CHEMBL70059 | C27H40N8O5 | 556.668 | 8 / 5 | 2.2 | No |
| 4519 |  CHEMBL553037 | C27H40N8O5 | 556.668 | 8 / 5 | 2.2 | No |
| 4588 |  CHEMBL79201 | C14H14N6OS | 314.367 | 6 / 2 | 1.2 | Yes |
| 4748 |  CHEMBL27376 | C20H20ClIN6O3 | 554.773 | 7 / 4 | 2.0 | No |
| 5005 |  CHEMBL1790736 | C16H22ClN5O3 | 367.834 | 7 / 3 | 3.3 | Yes |
| 5156 |  CHEMBL1095693 | C12H12N2OS | 232.301 | 3 / 0 | 1.8 | Yes |
| 5266 |  CHEMBL164039 | C24H29NO4S2 | 459.619 | 7 / 0 | 5.6 | No |
| 5373 |  CHEMBL3093315 | C17H17N5O2S | 355.416 | 5 / 0 | 1.4 | Yes |
| 5631 |  2-(1-hexynyl)adenosine | C16H21N5O4 | 347.375 | 8 / 4 | 1.3 | Yes |
| 5658 |  FR-166124 | C25H22N4O3 | 426.476 | 5 / 1 | 2.9 | Yes |
| 5801 |  CHEMBL392115 | C19H23N5O3 | 369.425 | 5 / 1 | 1.4 | Yes |
| 521634 |  CHEMBL3828530 | C20H26N6O3 | 398.467 | 6 / 0 | 1.7 | Yes |
| 5868 |  CHEMBL72287 | C22H16N2O | 324.383 | 3 / 0 | 4.0 | Yes |
| 5945 |  CHEMBL268964 | C13H12ClN5O2 | 305.722 | 4 / 2 | 2.2 | Yes |
| 6101 |  CHEMBL2374412 | C19H24N6O4 | 400.439 | 9 / 5 | 1.6 | Yes |
| 6106 |  CHEMBL604764 | C21H25N5O4 | 411.462 | 8 / 4 | 2.3 | Yes |
| 463613 |  CHEMBL2235589 | C21H25N5O4 | 411.462 | 8 / 4 | 2.3 | Yes |
| 6539 |  CHEMBL1092868 | C16H13N7O2S | 367.387 | 7 / 2 | 2.4 | Yes |
| 6584 |  CHEMBL431370 | C11H12N4 | 200.245 | 2 / 2 | 2.0 | Yes |
| 6644 |  CHEMBL27773 | C17H11BrN2O2 | 355.191 | 3 / 0 | 4.4 | Yes |
| 6719 |  CHEMBL608327 | C18H18ClIN6O4 | 544.734 | 8 / 4 | 1.5 | No |
| 6730 |  MRS 1754 | C26H26N6O4 | 486.532 | 6 / 2 | 4.9 | Yes |
| 6755 |  CHEMBL603992 | C25H27N5O4S | 493.582 | 9 / 4 | 4.4 | Yes |
| 6959 |  CHEMBL387319 | C18H23N7O2 | 369.429 | 8 / 2 | 1.1 | Yes |
| 6993 |  1,3-DibutylX-7-riboside | C18H35N5O4 | 385.509 | 8 / 4 | -0.3 | Yes |
| 7077 |  CHEMBL286479 | C17H12BrN3O2 | 370.206 | 4 / 1 | 3.7 | Yes |
| 7228 |  CHEMBL424433 | C15H20N4O4 | 320.349 | 5 / 0 | 0.9 | Yes |
| 7293 |  CID 71508724 | C15H23N7O8 | 429.39 | 14 / 9 | -2.7 | No |
| 7420 |  CHEMBL380914 | C19H19Cl2N7O5 | 496.305 | 8 / 5 | 1.3 | Yes |
| 7701 |  CHEMBL56813 | C15H18N4OS2 | 334.456 | 4 / 1 | 3.4 | Yes |
| 7804 |  CHEMBL2113585 | C28H33N7O4 | 531.617 | 8 / 4 | 2.5 | No |
| 7911 |  CHEMBL27502 | C17H23N5O2 | 329.404 | 6 / 3 | 1.5 | Yes |
| 7946 |  CHEMBL562427 | C25H27N5O6 | 493.52 | 7 / 3 | 3.3 | Yes |
| 8048 |  CHEMBL561364 | C27H29N5O6 | 519.558 | 7 / 2 | 3.3 | No |
| 8223 |  CHEMBL337503 | C30H31N2O5S+ | 531.647 | 6 / 0 | 5.4 | No |
| 8497 |  CHEMBL66811 | C24H19N7O2 | 437.463 | 7 / 1 | 3.6 | Yes |
| 8514 |  CHEMBL206807 | C22H27N7O6 | 485.501 | 9 / 5 | 0.6 | Yes |
| 8517 |  CHEMBL610394 | C22H27N7O6 | 485.501 | 9 / 5 | 0.6 | Yes |
| 8762 |  CHEMBL22042 | C18H28N4O2 | 332.448 | 3 / 0 | 3.6 | Yes |
| 8859 |  CHEMBL608748 | C20H29N5O5 | 419.482 | 7 / 5 | 1.0 | Yes |
| 8945 |  CHEMBL2111718 | C23H25N5O2 | 403.486 | 6 / 2 | 4.7 | Yes |
| 9034 |  CHEMBL184641 | C21H23F2N9O | 455.474 | 11 / 2 | 2.8 | No |
| 463982 |  CHEMBL2235585 | C23H29N5O5 | 455.515 | 9 / 4 | 2.7 | Yes |
| 9056 |  CHEMBL603927 | C23H29N5O5 | 455.515 | 9 / 4 | 2.7 | Yes |
| 9128 |  172516-44-8 | C17H24O3S2 | 340.496 | 5 / 0 | 5.3 | No |
| 9278 |  CHEMBL363647 | C19H18N6O2 | 362.393 | 6 / 2 | 2.0 | Yes |
| 9501 |  CHEMBL408489 | C23H32N6O3S | 472.608 | 6 / 2 | 4.3 | Yes |
| 9503 |  CHEMBL54505 | C24H30N6O3 | 450.543 | 7 / 3 | 2.9 | Yes |
| 9727 |  CHEMBL7897 | C15H15N5O4S | 361.376 | 7 / 2 | N/A | N/A |
| 10015 |  CHEMBL223321 | C23H27ClF3N11O | 565.99 | 13 / 2 | 2.9 | No |
| 10038 |  CHEMBL2113603 | C29H31N7O4 | 541.612 | 8 / 4 | 2.7 | No |
| 10152 |  CHEMBL2113426 | C19H23N5O3S | 401.485 | 8 / 3 | 2.3 | Yes |
| 459308 |  CHEMBL2158244 | C15H10FNO2S | 287.308 | 4 / 1 | 2.8 | Yes |
| 10227 |  CHEMBL413046 | C26H31N7O6 | 537.577 | 9 / 5 | 2.0 | No |
| 10309 |  CHEMBL177386 | C19H19Cl2N9O | 460.323 | 9 / 2 | 2.9 | Yes |
| 10339 |  CHEMBL609543 | C14H21N5O5 | 339.352 | 9 / 4 | -0.5 | Yes |
| 10449 |  SB 204070 hydrochloride | C19H27ClN2O4 | 382.885 | 6 / 1 | 3.5 | Yes |
| 10653 |  CHEMBL315562 | C16H11FN8O | 350.317 | 8 / 1 | 2.3 | Yes |
| 10667 |  CHEMBL444281 | C25H27N5O5 | 477.521 | 6 / 3 | 4.8 | Yes |
| 10998 |  CHEMBL2113407 | C18H24N6O5 | 404.427 | 9 / 5 | -0.8 | Yes |
| 11027 |  3-Isobutyl-1-methylxanthine | C10H14N4O2 | 222.248 | 3 / 1 | 1.5 | Yes |
| 11034 |  CHEMBL2113469 | C19H29N5O3S | 407.533 | 8 / 3 | 3.0 | Yes |
| 11038 |  CHEMBL303883 | C15H17N5 | 267.336 | 4 / 0 | 3.3 | Yes |
| 11135 |  CHEMBL163813 | C26H34ClNO3S | 476.072 | 5 / 0 | 8.2 | No |
| 11172 |  CHEMBL612218 | C16H16ClN5O4 | 377.785 | 8 / 4 | 1.8 | Yes |
| 11294 |  2-(furan-2-yl)-5-(methylthio)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine | C9H8N6OS | 248.264 | 7 / 1 | 1.1 | Yes |
| 11351 |  CHEMBL606228 | C19H28N4O4 | 376.457 | 7 / 4 | 2.8 | Yes |
| 11440 |  CHEMBL2113704 | C16H15IN6 | 418.242 | 5 / 1 | 2.7 | Yes |
| 11519 |  CHEMBL2113685 | C16H18IN5O2S | 471.317 | 7 / 3 | 2.0 | Yes |
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