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●BioLiP ●HPmod ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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GPCR

Name	Calcitonin receptor
Species	Homo sapiens (Human)
Gene	CALCR
Synonym	CTRI1- CTR2 CTR CT-R CT receptor calcitonin receptor C1A/C1B [ Show all ]
Disease	Pain; Postmenopausal osteoporosis Paget's disease Hypertension Osteoporosis
Length	508
Amino acid sequence	MQFSGEKISGQRDLQKSKMRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRKLTTIFPLNWKYRKALSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQEPRNEPANNQGEESAEIIPLNIIEQESSA
UniProt	P30988
Protein Data Bank	6niy, 5ii0
GPCR-HGmod model	P30988
3D structure model	This structure is from PDB ID 6niy.
BioLiP	BL0346076,BL0346077,BL0346078, BL0438754
Therapeutic Target Database	T32247
ChEMBL	CHEMBL1832
IUPHAR	43
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
18026	CHEMBL2369907	C145H242N44O48S2	3433.91	55 / 53	-18.5	No
108614	CHEMBL294095	C14H13FN2O4S	324.326	5 / 1	0.7	Yes
110726	BMS-694153	C35H45FN8O3	644.796	6 / 3	3.6	No
113888	BDBM50422415	C149H222N38O44S3	3345.82	50 / 44	-10.7	No
130548	MK-8825	C31H30F2N6O3	572.617	8 / 3	1.9	No
187600	CHEMBL2369892	C150H227N39O44S3	3376.88	51 / 46	-11.3	No
187601	CGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAP-amide	C150H227N39O44S3	3376.88	51 / 46	-11.3	No
190393	CHEMBL2369899	C152H229N39O43S3	3386.91	50 / 45	-9.7	No
190395	D03DPD	C152H229N39O43S3	3386.91	50 / 45	-9.7	No
203788	CHEMBL60066	C12H8ClFN2O2	266.656	3 / 1	1.8	Yes
225992	CGNLSTCMLGTYTQDFNKPHTFPQTAIGVGAP-amide	C146H225N39O44S3	3326.81	51 / 45	-12.5	No
225995	CHEMBL2369905	C146H225N39O44S3	3326.81	51 / 45	-12.5	No
230441	D0A8VZ	C152H229N39O43S2	3354.85	49 / 45	-9.2	No
230444	CHEMBL2369893	C152H229N39O43S2	3354.85	49 / 45	-9.2	No
232345	CGNLSTCBLGTYTQDFNKFHZYPQTAIGVGAP-amide	C152H231N39O44S2	3372.87	50 / 46	-9.3	No
232347	CHEMBL2369897	C152H231N39O44S2	3372.87	50 / 46	-9.3	No
243836	CHEMBL61835	C13H11FN2O4S	310.299	5 / 1	0.4	Yes
262414	CHEMBL2369904	C146H225N39O44S3	3326.81	51 / 45	-12.5	No
262417	D0Y0NM	C146H225N39O44S3	3326.81	51 / 45	-12.5	No
265577	CHEMBL2369895	C144H241N43O48S2	3406.89	54 / 52	-18.7	No
265580	CSNLSTCVLGKLSQELc[DKLQK]YPRTNTGSGTP-amide	C144H241N43O48S2	3406.89	54 / 52	-18.7	No
314692	CHEMBL62108	C17H17FN2O4S	364.391	5 / 1	1.6	Yes
335513	D00JEO	C146H243N45O47S2	3444.94	55 / 52	-17.7	No
335514	CHEMBL2369912	C146H243N45O47S2	3444.94	55 / 52	-17.7	No
352696	CHEMBL3099899	C26H21Cl2N3O3	494.372	5 / 1	5.0	Yes
401265	CHEMBL58619	C19H15FN2O4S	386.397	5 / 1	1.9	Yes
414771	CHEMBL2369915	C146H244N44O47S2	3431.94	54 / 52	-16.8	No
416693	CHEMBL2369886	C145H241N45O47S2	3430.91	55 / 52	-18.0	No
416696	CSNLSTCVLGKLSQELc[DKLHO]YPRTNTGSGTP-amide	C145H241N45O47S2	3430.91	55 / 52	-18.0	No
422262	CHEMBL2369898	C142H216N38O44S3	3255.69	50 / 44	-12.7	No
555427	AC 187	C127H205N37O40	2890.26	44 / 44	-13.2	No

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