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GLASS

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	Melanocortin receptor 3
Species	Rattus norvegicus (Rat)
Gene	Mc3r
Synonym	gamma-MSH receptor MC3 receptor MC3-R melanocortin receptor 3
Disease	N/A for non-human GPCRs
Length	323
Amino acid sequence	MNSSCCPSSSYPTLPNLSQHPAAPSASNRSGSGFCEQVFIKPEVFLALGIVSLMENILVILAVVRNGNLHSPMYFFLCSLAAADMLVSLSNSLETIMIVVINSDSLTLEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALSLIVAIWVCCGICGVMFIVYSESKMVIVCLITMFFAMVLLMGTLYIHMFLFARLHVQRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFKEILCGCNGMNVG
UniProt	P32244
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4023
IUPHAR	284
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
23004	CHEMBL406891	C52H67N15O9S2	1110.32	14 / 14	-0.2	No
41143	CHEMBL393576	C30H40Cl2FN5O2	592.581	6 / 2	4.4	No
70834	CHEMBL415200	C50H63N13O9S2	1054.26	14 / 12	-0.2	No
112972	CHEMBL411378	C52H67N15O9S2	1110.32	14 / 14	-0.2	No
114539	CHEMBL407845	C51H65N15O9S2	1096.3	14 / 14	-0.6	No
114541	CHEMBL405087	C51H65N15O9S2	1096.3	14 / 14	-0.6	No
114550	CHEMBL410404	C51H65N15O9S2	1096.3	14 / 14	-0.6	No
116349	CHEMBL411400	C53H69N15O9S2	1124.35	14 / 14	0.0	No
117741	THIQ	C33H41ClN6O2	589.181	5 / 2	5.9	No
172823	MK-0489	C34H44ClF2N3O2	600.192	5 / 1	5.8	No
215932	CHEMBL2372365	C52H67N13O9S2	1082.31	14 / 13	0.6	No
554503	SHU9119	C54H71N15O9	1074.26	13 / 12	0.6	No
254196	CHEMBL414965	C55H72N16O10	1117.28	13 / 15	-0.9	No
301465	CHEMBL497746	C29H40ClFN4O2	531.113	5 / 1	5.0	No
331828	Ac-Ser-Tyr-Ser-Nle4-Glu-His-DPhe7-Arg-Trp-Gly-Lys-Pro-Val-NH2	C78H111N21O19	1646.87	22 / 22	-3.9	No
385940	CHEMBL406842	C51H64ClN15O9S2	1130.74	14 / 14	0.1	No
407243	CHEMBL368876	C31H48FN5O3	557.755	6 / 3	3.9	No
441392	CHEMBL405791	C55H67N15O9S2	1146.36	14 / 14	0.7	No

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