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| Name | Kappa-type opioid receptor |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Oprk1 |
| Synonym | MSL-1 KOR-1 KOPr KOP Kappa receptor [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 380 |
| Amino acid sequence | MESPIQIFRGDPGPTCSPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLESAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRVRNTVQDPASMRDVGGMNKPV |
| UniProt | P33534 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL4329 |
| IUPHAR | 318 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 557340 |  SCHEMBL10316476 | C44H58N8O5 | 778.999 | 7 / 6 | 4.0 | No |
| 547916 |  CHEMBL3893631 | C44H58N8O5 | 778.999 | 7 / 6 | 4.0 | No |
| 547919 |  CHEMBL3925949 | C38H55N9O6 | 733.915 | 9 / 7 | -0.5 | No |
| 557347 |  SCHEMBL11932315 | C38H55N9O6 | 733.915 | 9 / 7 | -0.5 | No |
| 3358 |  CHEMBL317269 | C23H31NO4 | 385.504 | 5 / 1 | 2.5 | Yes |
| 3525 |  CHEMBL38576 | C21H24Cl2N2O | 391.336 | 2 / 0 | 4.6 | Yes |
| 3534 |  CHEMBL320882 | C21H24Cl2N2O | 391.336 | 2 / 0 | 4.6 | Yes |
| 553265 |  Dynorphin B | C74H115N21O17 | 1570.86 | 21 / 22 | -3.6 | No |
| 5614 |  CHEMBL108344 | C21H22Cl2N2O | 389.32 | 2 / 0 | 4.4 | Yes |
| 8667 |  CHEMBL437242 | C46H73N15O9 | 980.186 | 12 / 14 | -2.1 | No |
| 9603 |  CHEMBL2163544 | C26H29N3O4 | 447.535 | 6 / 4 | 0.5 | Yes |
| 10199 |  CHEMBL326540 | C22H28N2O2 | 352.478 | 3 / 0 | 2.5 | Yes |
| 11329 |  Norbinaltorphimine | C40H43N3O6 | 661.799 | 8 / 5 | 3.2 | No |
| 11347 |  CHEMBL93614 | C22H29NO2 | 339.479 | 3 / 2 | 4.5 | Yes |
| 15507 |  CHEMBL107358 | C15H22Cl2N2O | 317.254 | 2 / 1 | 3.5 | Yes |
| 15708 |  CHEMBL2419124 | C30H30ClN3O4 | 532.037 | 6 / 3 | 2.8 | No |
| 557746 |  SCHEMBL10316471 | C35H53N11O4 | 691.882 | 7 / 8 | 0.5 | No |
| 548071 |  CHEMBL3958575 | C35H53N11O4 | 691.882 | 7 / 8 | 0.5 | No |
| 19003 |  CHEMBL520557 | C29H30N2O3 | 454.57 | 4 / 2 | 3.6 | Yes |
| 19014 |  BDBM85541 | C28H35NO4 | 449.591 | 5 / 2 | 3.6 | Yes |
| 19016 |  BDBM85540 | C28H35NO4 | 449.591 | 5 / 2 | 3.6 | Yes |
| 19801 |  CHEMBL98626 | C22H28ClNO | 357.922 | 2 / 1 | 6.1 | No |
| 20074 |  CHEMBL105923 | C22H26Cl2N2O2 | 421.362 | 3 / 0 | 4.6 | Yes |
| 21205 |  CHEMBL2437062 | C27H27N3O5 | 473.529 | 6 / 1 | 3.1 | Yes |
| 23257 |  CHEMBL2114080 | C17H25NO2 | 275.392 | 3 / 0 | 3.7 | Yes |
| 23815 |  CHEMBL110190 | C22H26Cl2N2OS | 437.423 | 3 / 0 | 5.1 | No |
| 24366 |  CHEMBL298314 | C26H27NO5 | 433.504 | 6 / 2 | 2.6 | Yes |
| 24761 |  CHEMBL611413 | C24H33NO4 | 399.531 | 5 / 0 | 2.9 | Yes |
| 25126 |  CHEMBL109115 | C20H32N2O | 316.489 | 2 / 0 | 4.1 | Yes |
| 25196 |  CHEMBL326899 | C21H24Cl2N2O | 391.336 | 2 / 0 | 4.8 | Yes |
| 25233 |  CHEMBL97509 | C21H33NO | 315.501 | 2 / 1 | 6.2 | No |
| 25374 |  CHEMBL2418741 | C18H23NO4 | 317.385 | 5 / 2 | 1.2 | Yes |
| 26102 |  CHEMBL119473 | C22H32N2O2 | 356.51 | 3 / 0 | 3.1 | Yes |
| 27731 |  CHEMBL109205 | C19H28Cl2N2O | 371.346 | 2 / 0 | 4.9 | Yes |
| 27908 |  DIPPA | C22H23Cl2N3OS | 448.406 | 4 / 0 | 6.0 | No |
| 28337 |  CHEMBL308813 | C42H36Cl2N4O6S | 795.732 | 8 / 4 | 4.0 | No |
| 558191 |  SCHEMBL10316443 | C42H56N8O5 | 752.961 | 7 / 6 | 3.8 | No |
| 548215 |  CHEMBL3965992 | C42H56N8O5 | 752.961 | 7 / 6 | 3.8 | No |
| 30358 |  morphine | C17H19NO3 | 285.343 | 4 / 2 | 0.8 | Yes |
| 30529 |  CHEMBL2207678 | C22H27NO2 | 337.463 | 3 / 1 | 3.1 | Yes |
| 30888 |  CHEMBL522142 | C30H33FN2O4 | 504.602 | 6 / 2 | 2.0 | No |
| 31366 |  oxycodone | C18H21NO4 | 315.369 | 5 / 1 | 1.2 | Yes |
| 31546 |  CHEMBL106726 | C19H30N2O | 302.462 | 2 / 0 | 3.6 | Yes |
| 32224 |  CHEMBL303301 | C27H34N2O3 | 434.58 | 4 / 3 | 4.6 | Yes |
| 558341 |  SCHEMBL10316438 | C37H57N9O4 | 691.922 | 7 / 7 | 2.4 | No |
| 548297 |  CHEMBL3923450 | C37H57N9O4 | 691.922 | 7 / 7 | 2.4 | No |
| 467409 |  CHEMBL3613166 | C30H35ClN2O2 | 491.072 | 3 / 2 | N/A | N/A |
| 467412 |  CHEMBL3613170 | C30H35ClN2O2 | 491.072 | 3 / 2 | N/A | N/A |
| 43660 |  CHEMBL148020 | C18H25NO | 271.404 | 2 / 1 | 2.9 | Yes |
| 43661 |  CHEMBL357859 | C18H25NO | 271.404 | 2 / 1 | 2.9 | Yes |
| 46271 |  CHEMBL511773 | C31H34N2O3 | 482.624 | 4 / 1 | 4.3 | Yes |
| 558758 |  SCHEMBL10316452 | C42H55ClN8O5 | 787.403 | 7 / 6 | 4.4 | No |
| 548458 |  CHEMBL3971532 | C42H55ClN8O5 | 787.403 | 7 / 6 | 4.4 | No |
| 48739 |  CHEMBL485428 | C28H32N2O4S | 492.634 | 6 / 2 | 1.6 | Yes |
| 49022 |  CHEMBL458089 | C30H40N2O4 | 492.66 | 5 / 2 | 2.8 | Yes |
| 50081 |  CHEMBL2437067 | C26H25N3O5 | 459.502 | 6 / 2 | 2.7 | Yes |
| 50617 |  CHEMBL410611 | C47H74N16O11 | 1039.21 | 14 / 14 | -0.5 | No |
| 558878 |  SCHEMBL10316473 | C36H55N9O4 | 677.895 | 7 / 7 | 1.9 | No |
| 548489 |  CHEMBL3952303 | C36H55N9O4 | 677.895 | 7 / 7 | 1.9 | No |
| 52706 |  CHEMBL1770605 | C22H21NO3 | 347.414 | 4 / 0 | 4.6 | Yes |
| 52986 |  CHEMBL2163546 | C26H28N2O5 | 448.519 | 6 / 4 | 0.8 | Yes |
| 469450 |  CHEMBL3613163 | C30H35ClN2O3 | 507.071 | 4 / 2 | N/A | No |
| 469453 |  CHEMBL3613167 | C30H35ClN2O3 | 507.071 | 4 / 2 | N/A | No |
| 53184 |  CHEMBL611146 | C22H29NO4 | 371.477 | 5 / 0 | 2.4 | Yes |
| 53473 |  CHEMBL297933 | C29H31NO5 | 473.569 | 6 / 2 | 3.7 | Yes |
| 56061 |  CHEMBL476540 | C28H28N2O3 | 440.543 | 4 / 2 | 3.2 | Yes |
| 56211 |  CHEMBL110834 | C17H26N2O | 274.408 | 2 / 1 | 3.1 | Yes |
| 57787 |  CHEMBL2164300 | C26H36N2O4 | 440.584 | 5 / 3 | 2.0 | Yes |
| 59195 |  CHEMBL330138 | C19H25NOS | 315.475 | 3 / 1 | 4.8 | Yes |
| 60043 |  CHEMBL148086 | C17H22N2O | 270.376 | 3 / 1 | 1.5 | Yes |
| 60046 |  CHEMBL149491 | C17H22N2O | 270.376 | 3 / 1 | 1.5 | Yes |
| 559132 |  SCHEMBL10316439 | C37H55N7O6 | 693.89 | 9 / 7 | -0.1 | No |
| 548601 |  CHEMBL3932640 | C37H55N7O6 | 693.89 | 9 / 7 | -0.1 | No |
| 60293 |  CHEMBL611415 | C24H33NO3 | 383.532 | 4 / 0 | 3.3 | Yes |
| 61781 |  SCHEMBL1651439 | C28H33ClN2O5 | 513.031 | 7 / 3 | N/A | No |
| 62334 |  BU-46 | C26H31NO4 | 421.537 | 5 / 2 | 2.8 | Yes |
| 62336 |  BU-47 | C26H31NO4 | 421.537 | 5 / 2 | 2.8 | Yes |
| 62983 |  CHEMBL105942 | C19H28Cl2N2O | 371.346 | 2 / 0 | 4.9 | Yes |
| 63110 |  CHEMBL108076 | C24H33N3O2 | 395.547 | 3 / 2 | 3.8 | Yes |
| 66179 |  naltrexone | C20H23NO4 | 341.407 | 5 / 2 | 1.9 | Yes |
| 66994 |  CHEMBL431266 | C22H35NO | 329.528 | 2 / 1 | 6.6 | No |
| 67602 |  CHEMBL491075 | C29H32Cl2N2O4 | 543.485 | 5 / 2 | 2.7 | No |
| 67604 |  CHEMBL523151 | C29H32Cl2N2O4 | 543.485 | 5 / 2 | 2.7 | No |
| 67881 |  CHEMBL2418739 | C18H23NO3 | 301.386 | 4 / 2 | 2.3 | Yes |
| 67936 |  CHEMBL55705 | C22H24Cl2N2O | 403.347 | 2 / 0 | 5.1 | No |
| 68205 |  CHEMBL317097 | C20H27NOS | 329.502 | 3 / 1 | 5.1 | No |
| 70279 |  CHEMBL148588 | C28H39N9O6 | 597.677 | 8 / 9 | -0.3 | No |
| 471785 |  CHEMBL3613168 | C42H54N2O6S | 714.962 | 7 / 2 | N/A | No |
| 471964 |  CHEMBL3604278 | C27H35N3O2 | 433.596 | 4 / 0 | 4.3 | Yes |
| 74830 |  CHEMBL323472 | C23H27Cl2N3O2 | 448.388 | 3 / 1 | 3.8 | Yes |
| 77596 |  CHEMBL1795711 | C27H29IN2O4 | 572.443 | 5 / 3 | 1.9 | No |
| 559787 |  SCHEMBL10316441 | C34H51N9O4 | 649.841 | 7 / 7 | 1.1 | No |
| 548841 |  CHEMBL3978743 | C34H51N9O4 | 649.841 | 7 / 7 | 1.1 | No |
| 81052 |  CHEMBL469027 | C30H32N2O3 | 468.597 | 4 / 2 | 3.9 | Yes |
| 82723 |  CHEMBL108618 | C18H27ClN2O | 322.877 | 2 / 0 | 3.9 | Yes |
| 84655 |  CHEMBL2164296 | C27H27F3N2O5 | 516.517 | 9 / 3 | 2.4 | No |
| 87352 |  CHEMBL1770606 | C22H21NO3 | 347.414 | 4 / 0 | 4.6 | Yes |
| 88428 |  CHEMBL611145 | C23H31NO4 | 385.504 | 5 / 0 | 2.5 | Yes |
| 548952 |  CHEMBL3970706 | C36H53N7O6 | 679.863 | 9 / 7 | -0.6 | No |
| 560032 |  Difelikefalin | C36H53N7O6 | 679.863 | 9 / 7 | -0.6 | No |
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