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| Name | Type-2 angiotensin II receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Agtr2 |
| Synonym | angiotensin II receptor, type 2 MRX88 Agtr2 AT2R AT2-R [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 363 |
| Amino acid sequence | MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS |
| UniProt | P35351 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL257 |
| IUPHAR | 35 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 103 |  CHEMBL338434 | C36H41F4N5O6S | 747.807 | 11 / 2 | 7.3 | No |
| 140 |  CHEMBL338740 | C27H22Cl2N6O2 | 533.413 | 6 / 2 | 7.0 | No |
| 754 |  CHEMBL350554 | C37H38N4O6S | 666.793 | 7 / 1 | 6.3 | No |
| 1134 |  CHEMBL166428 | C33H37N3O6S | 603.734 | 7 / 2 | 4.8 | No |
| 1608 |  CHEMBL94582 | C27H24ClF3N4O4S | 593.018 | 8 / 1 | 6.1 | No |
| 3234 |  CHEMBL98665 | C43H47FN4O6S | 766.929 | 8 / 1 | 8.9 | No |
| 3539 |  CHEMBL74476 | C35H43N5O6S | 661.818 | 7 / 2 | 5.8 | No |
| 3735 |  CHEMBL319730 | C37H37Cl2N5O5S | 734.693 | 6 / 2 | 7.7 | No |
| 3821 |  CHEMBL62754 | C30H42N4O5 | 538.689 | 5 / 1 | 5.3 | No |
| 4360 |  CHEMBL132408 | C27H24N8O | 476.544 | 6 / 1 | 4.7 | Yes |
| 7481 |  CHEMBL61976 | C24H26N6O | 414.513 | 5 / 1 | 4.6 | Yes |
| 7959 |  CHEMBL328602 | C41H46N6O6S | 750.915 | 9 / 1 | 6.6 | No |
| 8686 |  CHEMBL276853 | C36H33N7O2 | 595.707 | 6 / 1 | 6.2 | No |
| 9363 |  CHEMBL337006 | C34H35N5O3S | 593.746 | 6 / 1 | 6.8 | No |
| 9467 |  CHEMBL322471 | C36H35N7O3 | 613.722 | 7 / 1 | 6.2 | No |
| 9667 |  CHEMBL352503 | C34H40N4O6S | 632.776 | 7 / 2 | 5.8 | No |
| 10034 |  CHEMBL124771 | C33H37BrFN5O6S | 730.65 | 8 / 2 | 6.2 | No |
| 10456 |  CHEMBL329693 | C33H31F3N4O5S | 652.689 | 9 / 1 | 7.1 | No |
| 10864 |  CHEMBL165541 | C34H42N4O4S | 602.794 | 6 / 2 | 5.3 | No |
| 11332 |  CHEMBL15517 | C26H26ClN3O3 | 463.962 | 5 / 1 | 6.1 | No |
| 12291 |  CHEMBL88170 | C35H35N7O3 | 601.711 | 7 / 1 | 6.6 | No |
| 12348 |  CHEMBL306641 | C32H40N6O4S | 604.77 | 6 / 3 | 5.3 | No |
| 12479 |  CHEMBL15730 | C26H27N3O3 | 429.52 | 5 / 1 | 5.5 | No |
| 12481 |  CHEMBL74144 | C35H34FN5O6S | 671.744 | 9 / 2 | 5.5 | No |
| 12811 |  CHEMBL62157 | C27H52N4O4 | 496.737 | 4 / 1 | 5.8 | No |
| 12862 |  CHEMBL134567 | C27H26Cl2N4O2 | 509.431 | 5 / 1 | 6.3 | No |
| 12945 |  CHEMBL122157 | C31H33BrFN5O6S | 702.596 | 8 / 2 | 5.3 | No |
| 13345 |  CHEMBL167662 | C35H35N3O4S | 593.742 | 5 / 1 | 6.9 | No |
| 13955 |  CHEMBL304947 | C37H47N5O4S | 657.874 | 6 / 2 | 7.8 | No |
| 14362 |  CHEMBL436396 | C32H35BrFN5O6S | 716.623 | 8 / 2 | 5.6 | No |
| 15540 |  CHEMBL321313 | C33H37ClFN5O6S | 686.196 | 8 / 2 | 6.4 | No |
| 16066 |  CHEMBL304022 | C28H34ClN3O6S | 576.105 | 7 / 1 | 6.5 | No |
| 16515 |  CHEMBL290669 | C39H33N7O2 | 631.74 | 6 / 1 | 6.8 | No |
| 17191 |  CHEMBL353615 | C34H41N5O6S | 647.791 | 7 / 3 | 5.5 | No |
| 17261 |  CHEMBL335066 | C29H34N4O2 | 470.617 | 5 / 1 | 6.6 | No |
| 17790 |  4-[(2-Butyl-1H-benzimidazol-1-yl)methyl]benzoic acid | C19H20N2O2 | 308.381 | 3 / 1 | 4.3 | Yes |
| 18113 |  CHEMBL316904 | C34H31F3N4O5S | 664.7 | 9 / 1 | 6.9 | No |
| 18764 |  CHEMBL311386 | C34H40FN5O6S | 665.781 | 8 / 2 | 4.5 | No |
| 19639 |  CHEMBL139325 | C39H33Cl2N5O5S | 754.683 | 6 / 2 | 8.1 | No |
| 20478 |  CHEMBL316482 | C31H33F3N4O5S | 630.683 | 9 / 1 | 6.9 | No |
| 21431 |  CHEMBL214671 | C27H29N3O5S2 | 539.665 | 7 / 1 | 5.6 | No |
| 22257 |  CHEMBL265291 | C32H29N7O3 | 559.63 | 7 / 2 | 5.4 | No |
| 23828 |  CHEMBL42101 | C38H34N8O2 | 634.744 | 6 / 1 | 6.8 | No |
| 24993 |  CHEMBL290768 | C37H31N7O2S | 637.762 | 7 / 1 | 6.8 | No |
| 25001 |  CHEMBL140619 | C37H38ClN5O5S | 700.251 | 6 / 2 | 7.2 | No |
| 26251 |  CHEMBL299897 | C31H34N4O3S2Si | 602.843 | 6 / 1 | N/A | No |
| 26720 |  CHEMBL108981 | C37H37N7O3 | 627.749 | 7 / 1 | 6.6 | No |
| 26817 |  CHEMBL15729 | C28H28ClN3O3 | 490.0 | 5 / 1 | 6.9 | No |
| 28048 |  CHEMBL97075 | C33H28F6N4O5S | 706.66 | 12 / 1 | 7.3 | No |
| 29134 |  CHEMBL139452 | C36H36Cl2N6O5S | 735.681 | 6 / 3 | 7.2 | No |
| 29481 |  CHEMBL64861 | C29H39BrN4O4 | 587.559 | 4 / 1 | 6.0 | No |
| 29685 |  CHEMBL316273 | C32H33F3N4O4S | 626.695 | 8 / 1 | 6.8 | No |
| 30273 |  CHEMBL61754 | C23H23ClN6O | 434.928 | 5 / 1 | 4.9 | Yes |
| 30840 |  CHEMBL169221 | C32H37N5O6S | 619.737 | 7 / 3 | 4.6 | No |
| 30849 |  CHEMBL334300 | C33H38ClN5O6S | 668.206 | 7 / 2 | 6.0 | No |
| 32476 |  CHEMBL336808 | C29H34N4O2 | 470.617 | 5 / 1 | 6.6 | No |
| 33359 |  CHEMBL335722 | C34H37N5O3S | 595.762 | 6 / 1 | 7.1 | No |
| 33602 |  CHEMBL90663 | C36H35N5O5 | 617.706 | 7 / 1 | 6.9 | No |
| 34791 |  CHEMBL71925 | C38H35N9O | 633.76 | 6 / 2 | 7.5 | No |
| 35359 |  CHEMBL327569 | C33H28F3N5O4S | 647.673 | 10 / 1 | 7.2 | No |
| 35760 |  CHEMBL59728 | C28H34N4O8S | 586.66 | 9 / 1 | 5.7 | No |
| 37734 |  CHEMBL93606 | C32H36F3N5O4S | 643.726 | 9 / 2 | 5.3 | No |
| 37916 |  CHEMBL320222 | C33H25ClF6N4O4S | 723.087 | 11 / 1 | 7.9 | No |
| 38641 |  CHEMBL94176 | C34H29F3N4O4S | 646.685 | 8 / 1 | 6.8 | No |
| 39486 |  CHEMBL47382 | C23H22N8 | 410.485 | 6 / 1 | 3.6 | Yes |
| 40785 |  CHEMBL339672 | C35H32Cl2FN5O5S | 724.629 | 7 / 2 | 7.0 | No |
| 40874 |  CHEMBL341934 | C36H35Cl2N5O5S | 720.666 | 6 / 2 | 7.3 | No |
| 42684 |  CHEMBL352502 | C37H38N4O6S | 666.793 | 7 / 2 | 6.5 | No |
| 43228 |  CHEMBL329290 | C32H27Cl4F3N4O5S | 778.446 | 9 / 1 | N/A | No |
| 43365 |  CHEMBL95198 | C32H29F3N4O5S | 638.662 | 9 / 1 | 6.4 | No |
| 43477 |  CHEMBL37679 | C23H23ClN2O4S | 458.957 | 6 / 2 | 5.1 | No |
| 43604 |  CHEMBL12810 | C22H28N8 | 404.522 | 5 / 1 | 4.7 | Yes |
| 44379 |  CHEMBL330463 | C34H31F3N4O5S | 664.7 | 9 / 1 | 6.9 | No |
| 45521 |  CHEMBL71485 | C27H29N3O2 | 427.548 | 4 / 1 | 5.7 | No |
| 46617 |  CHEMBL306362 | C36H42FN5O6S | 691.819 | 8 / 2 | 6.1 | No |
| 46658 |  CHEMBL431162 | C27H32FN3O5S | 529.627 | 7 / 1 | 5.6 | No |
| 47321 |  CHEMBL340367 | C37H41N3O4 | 591.752 | 6 / 1 | 9.4 | No |
| 48094 |  CHEMBL98453 | C31H25Br2F3N4O4S2 | 798.488 | 9 / 1 | 8.6 | No |
| 48524 |  CHEMBL136034 | C27H29ClN4O2 | 477.005 | 5 / 1 | 6.3 | No |
| 48842 |  CHEMBL338888 | C33H37ClFN5O6S | 686.196 | 8 / 2 | 6.1 | No |
| 48895 |  CHEMBL39349 | C23H24N2O4S | 424.515 | 6 / 2 | 4.5 | Yes |
| 48903 |  CHEMBL337588 | C35H32Cl2N4O6S | 707.623 | 7 / 1 | 7.5 | No |
| 49331 |  CHEMBL354080 | C34H41N5O6S | 647.791 | 7 / 3 | 5.4 | No |
| 49604 |  CHEMBL300154 | C32H34N4O3S2 | 586.769 | 6 / 1 | 7.6 | No |
| 50862 |  CHEMBL350851 | C26H30N4O5S | 510.609 | 7 / 2 | 4.6 | No |
| 52510 |  CHEMBL121872 | C34H39BrFN5O6S | 744.677 | 8 / 2 | 6.5 | No |
| 53209 |  CHEMBL138690 | C33H30Cl3N5O6S | 731.042 | 7 / 2 | 6.9 | No |
| 53211 |  CHEMBL331632 | C35H33ClFN5O6S | 706.186 | 8 / 2 | 6.4 | No |
| 53839 |  CHEMBL352629 | C33H39N5O7S | 649.763 | 8 / 3 | 4.2 | No |
| 53949 |  L-158338 | C24H23N7 | 409.497 | 5 / 1 | 4.7 | Yes |
| 54474 |  CHEMBL136465 | C37H37Cl2N5O5S | 734.693 | 6 / 2 | 7.8 | No |
| 54966 |  CHEMBL98426 | C32H32Cl3F3N4O4S | 732.037 | 8 / 1 | N/A | No |
| 56093 |  CHEMBL408799 | C40H42N4O6S | 706.858 | 7 / 1 | 6.7 | No |
| 56962 |  CHEMBL74556 | C36H44FN5O6S | 693.835 | 8 / 2 | 6.3 | No |
| 57083 |  CHEMBL68638 | C31H36N4O3S | 544.714 | 5 / 1 | 6.8 | No |
| 57388 |  CHEMBL338101 | C37H37Cl2N5O5S | 734.693 | 6 / 2 | 7.8 | No |
| 57656 |  CHEMBL125760 | C32H35ClFN5O7S | 688.168 | 9 / 2 | 5.0 | No |
| 59068 |  CHEMBL97464 | C40H35F3N4O4S | 724.799 | 8 / 1 | 8.8 | No |
| 59117 |  CHEMBL431137 | C28H34ClN3O5S | 560.106 | 6 / 1 | 6.3 | No |
| 59683 |  CHEMBL350121 | C29H38N4O5S | 554.706 | 7 / 3 | 6.8 | No |
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