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You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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GPCR

Name	Histamine H2 receptor
Species	Cavia porcellus (Guinea pig)
Gene	HRH2
Synonym	Gastric receptor I H2R HH2R
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MAFNGTVPSFCMDFTVYKVTISVILIILILVTVAGNVVVCLAVGLNRRLRSLTNCFIVSLAVTDLLLGLLVLPFSAIYQLSCKWSFSKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLITPARVAISLVFIWVISITLSFLSIHLGWNSRNETSKDNDTIVKCKVQVNEVYGLVDGLVTFYLPLLIMCITYFRIFKIAREQARRINHIGSWKAATIREHKATVTLAAVMGAFIICWFPYFTVFVYRGLKGDDAVNEVFEDVVLWLGYANSALNPILYAALNRDFRTAYHQLFCCRLASHNSHETSLRLNNSQLNRSQCQEPRWQEDKPLNLQVWSGTEVTAPQGATNR
UniProt	P47747
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2882
IUPHAR	N/A
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
884	CHEMBL296448	C16H18N6	294.362	5 / 3	3.0	Yes
1085	CHEMBL161710	C21H28N2O	324.468	3 / 1	5.1	No
1708	CHEMBL339780	C15H16N4O4	316.317	6 / 4	N/A	N/A
2959	CID 44370594	C14H21N3O6	327.337	7 / 4	N/A	N/A
3176	CID 54587035	C20H25N9O7S2	567.596	12 / 4	N/A	No
3345	UR-AK68	C16H21N5O	299.378	3 / 3	2.1	Yes
535996	CHEMBL308685	C26H36N6O3S	512.673	7 / 3	3.3	No
3701	CHEMBL3220892	C17H23N5O	313.405	3 / 2	1.7	Yes
3767	83184-32-1	C11H9N5	211.228	3 / 2	1.2	Yes
4079	CHEMBL445384	C11H14N6O2S2	326.393	7 / 3	-0.7	Yes
536046	CHEMBL72243	C25H33N7O2	463.586	6 / 3	2.1	Yes
4472	UR-AK59	C16H27N5O	305.426	3 / 3	3.1	Yes
5298	CID 44323707	C15H22N2O5	310.35	6 / 3	N/A	N/A
5885	CHEMBL33996	C13H15N5O2	273.296	5 / 3	2.8	Yes
6497	CHEMBL128585	C17H21N3O2	299.374	3 / 2	2.7	Yes
7138	4-(1H-imidazol-4-yl)pyridine	C8H7N3	145.165	2 / 1	0.7	Yes
8239	CHEMBL341093	C14H14N4O4	302.29	6 / 4	N/A	N/A
8706	CHEMBL12059	C14H16N4S2	304.43	4 / 2	2.9	Yes
9318	CHEMBL158413	C17H20N6O2S	372.447	6 / 3	-0.3	Yes
9904	CHEMBL415989	C22H28N6O4	440.504	6 / 4	1.9	Yes
10119	135450-94-1	C12H14N6OS	290.345	5 / 3	-0.5	Yes
11656	BDBM50091375	C15H19N3O2	273.336	4 / 1	2.5	Yes
11789	cimetidine	C10H16N6S	252.34	4 / 3	0.4	Yes
12272	CHEMBL39603	C21H25NO2	323.436	3 / 0	3.8	Yes
13440	CHEMBL423473	C15H17IN2O2	384.217	3 / 1	3.1	Yes
14175	83184-12-7	C11H12N4	200.245	2 / 2	1.1	Yes
14236	180083-23-2	C32H32N4O3	520.633	6 / 0	5.6	No
442242	CHEMBL99356	C18H20N6O2S	384.458	6 / 3	0.8	Yes
15412	CHEMBL277227	C14H15IN2O2	370.19	3 / 1	2.8	Yes
15544	CHEMBL51541	C14H20Cl2N4	315.242	2 / 4	N/A	N/A
15763	CHEMBL20191	C13H13IN2O2	356.163	3 / 1	3.3	Yes
15990	124458-10-2	C5H9N3S	143.208	4 / 2	0.0	Yes
16200	BU-E-76	C21H24F2N6	398.462	5 / 3	2.5	Yes
17581	103851-74-7	C8H8N4	160.18	3 / 2	0.3	Yes
18090	CHEMBL299537	C15H20N4	256.353	2 / 2	2.5	Yes
18744	CHEMBL151676	C16H19N3	253.349	3 / 0	3.1	Yes
19223	CHEMBL431776	C14H21N7S	319.431	5 / 4	1.7	Yes
19726	CHEMBL131021	C20H24N2O6	388.42	7 / 3	N/A	N/A
19816	CHEMBL70623	C27H36N6O2	476.625	5 / 3	3.6	Yes
19981	CHEMBL43560	C10H14N6	218.264	5 / 3	1.8	Yes
20185	imipramine	C19H24N2	280.415	2 / 0	4.8	Yes
20229	CHEMBL3220888	C21H30N4O2	370.497	4 / 2	2.9	Yes
20247	CHEMBL499301	C21H23N5O	361.449	3 / 3	2.9	Yes
20530	CHEMBL79974	C20H33N3O2	347.503	3 / 2	3.3	Yes
442485	CHEMBL442171	C18H23F3N4O	368.404	6 / 3	2.8	Yes
20804	CHEMBL540005	C8H15N5	181.243	2 / 3	-0.4	Yes
21681	CHEMBL290613	C22H25NO6	399.443	7 / 2	N/A	N/A
21735	CHEMBL102215	C18H20FN	269.363	2 / 0	4.2	Yes
22337	CHEMBL61675	C21H25FN6	380.471	4 / 3	2.4	Yes
24433	CHEMBL128513	C19H22N2O6	374.393	7 / 3	N/A	N/A
24488	CID 44341209	C20H23N3O6	401.419	8 / 4	N/A	N/A
25914	CHEMBL71009	C27H36N10O3	548.652	9 / 3	5.9	No
26966	CHEMBL14868	C31H41N3O	471.689	4 / 1	7.3	No
27131	7-OH-DPAT	C16H25NO	247.382	2 / 1	4.1	Yes
27737	CHEMBL35869	C24H30N2O6	442.512	8 / 2	N/A	N/A
27790	UR-AK46	C14H23N5O	277.372	3 / 3	2.0	Yes
28067	CHEMBL78339	C18H28FN3O2	337.439	4 / 2	2.3	Yes
28797	CHEMBL59851	C23H23BrN2O5	487.35	6 / 3	N/A	N/A
29322	CID 44370355	C16H25N3O6	355.391	7 / 4	N/A	N/A
29621	CHEMBL3248393	C10H19ClN6OS	306.813	4 / 5	N/A	N/A
29844	BDBM50091371	C15H19N3O2	273.336	4 / 1	2.5	Yes
29947	CHEMBL311272	C23H31N3O2	381.52	3 / 2	3.9	Yes
30032	Histaprodifen	C20H23N3	305.425	2 / 2	3.5	Yes
30724	76721-87-4	C7H13N3	139.202	2 / 2	0.4	Yes
30802	CHEMBL132798	C15H16N2O	240.306	2 / 1	3.1	Yes
30967	CHEMBL3220884	C19H24N4O	324.428	3 / 2	2.9	Yes
31226	UR-PG55B	C22H23F2N5O	411.457	5 / 3	3.4	Yes
442894	103827-12-9	C17H22N4O2	314.389	3 / 3	1.1	Yes
31551	CID 44341348	C18H22N2O6	362.382	7 / 4	N/A	N/A
32007	CHEMBL70633	C26H35N7O2	477.613	6 / 4	2.5	Yes
32408	CHEMBL277149	C14H16ClN3O2	293.751	3 / 2	2.6	Yes
32671	SCHEMBL8106368	C11H18N2O	194.278	2 / 1	2.1	Yes
32745	CHEMBL12623	C14H16N4S2	304.43	4 / 2	3.0	Yes
32904	CHEMBL16496	C14H16IN3O2	385.205	3 / 2	2.6	Yes
32980	VUF-8406	C11H18N6S	266.367	4 / 3	0.7	Yes
33846	CHEMBL19172	C13H15BrN2O	295.18	2 / 1	2.8	Yes
33963	CHEMBL145671	C12H13N5OS	275.33	4 / 3	0.9	Yes
35784	CHEMBL50362	C11H20N6O2S2	332.441	6 / 3	-0.2	Yes
35819	CHEMBL356449	C27H30N4	410.565	3 / 2	4.9	Yes
36653	CID 44341037	C20H25N3O6	403.435	8 / 4	N/A	N/A
36767	CHEMBL3220886	C19H24N4O	324.428	3 / 2	2.9	Yes
37115	CHEMBL12527	C14H17N5S	287.385	3 / 3	1.8	Yes
37289	CHEMBL309401	C22H30N4O2	382.508	4 / 3	2.9	Yes
37805	triprolidine	C19H22N2	278.399	2 / 0	3.9	Yes
38673	SCHEMBL7977259	C7H12N2O	140.186	2 / 1	0.5	Yes
38744	CHEMBL297627	C40H42N6O7	718.811	10 / 5	1.8	No
38858	CHEMBL553806	C13H19ClN8O2S2	418.919	7 / 5	N/A	N/A
39980	CHEMBL298442	C10H13N5	203.249	4 / 2	1.4	Yes
40165	CHEMBL20686	C15H19IN2O	370.234	2 / 1	3.5	Yes
40426	CHEMBL418211	C14H22N6S2	338.492	5 / 3	1.2	Yes
41288	CHEMBL345173	C17H22N6OS	358.464	5 / 3	1.6	Yes
41399	CHEMBL291369	C21H22N2O5	382.416	6 / 3	N/A	N/A
41425	CHEMBL458718	C26H40N2	380.62	2 / 0	6.8	No
41443	CHEMBL323568	C20H23N5O3S	413.496	6 / 3	1.9	Yes
42539	Aminopotentidine	C26H35N7O2	477.613	6 / 4	2.5	Yes
42713	CHEMBL352164	C21H28N2O3S	388.526	5 / 1	4.1	Yes
43011	CHEMBL112753	C15H19N3O2	273.336	4 / 1	2.6	Yes
43050	CHEMBL87583	C15H16F3N3	295.309	5 / 2	3.0	Yes
43640	CHEMBL320650	C18H24N2O	284.403	3 / 0	3.6	Yes
44135	CID 44341092	C17H19N3O6	361.354	7 / 4	N/A	N/A

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