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Name | Melanocortin receptor 4 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Mc4r |
Synonym | MC4 receptor MC4-R |
Disease | N/A for non-human GPCRs |
Length | 332 |
Amino acid sequence | MNSTHHHGMYTSLHLWNRSSYGLHGNASESLGKGHPDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVSGVLFIIYSDSSAVIICLISMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGTNMKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPLIYALRSQELRKTFKEIICFYPLGGICELSSRY |
UniProt | P56450 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3719 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
463042 | ![]() | C51H66N12O9 | 991.164 | 10 / 9 | 1.0 | No |
5972 | ![]() | C70H85N17O16 | 1420.55 | 18 / 18 | -2.5 | No |
5976 | ![]() | C70H85N17O16 | 1420.55 | 18 / 19 | -2.2 | No |
8133 | ![]() | C24H31N5O2 | 421.545 | 3 / 5 | 1.7 | Yes |
10924 | ![]() | C64H78N14O14S2 | 1331.53 | 18 / 17 | -0.7 | No |
11090 | ![]() | C71H90N20O15S3 | 1559.81 | 33 / 22 | 4.0 | No |
521795 | ![]() | C46H67N13O10 | 962.123 | 13 / 11 | -1.4 | No |
12238 | ![]() | C50H69N15O10 | 1040.2 | 13 / 13 | 0.3 | No |
12396 | ![]() | C34H51FN4O3 | 582.805 | 5 / 2 | 5.4 | No |
15600 | ![]() | C31H36F3N9O4 | 655.683 | 9 / 7 | 1.5 | No |
16256 | ![]() | C33H42N12O5 | 686.778 | 8 / 9 | -1.1 | No |
18262 | ![]() | C33H29N3O2 | 499.614 | 2 / 1 | 5.9 | No |
522049 | ![]() | C74H101N23O16 | 1568.77 | 19 / 17 | -3.2 | No |
20120 | ![]() | C33H38ClF2N3O3 | 598.132 | 7 / 0 | 4.8 | No |
23001 | ![]() | C52H67N15O9S2 | 1110.32 | 14 / 14 | -0.2 | No |
26906 | ![]() | C25H32N6O2 | 448.571 | 4 / 5 | 2.4 | Yes |
28883 | ![]() | C53H73N15O11 | 1096.26 | 13 / 14 | -0.5 | No |
31251 | ![]() | C44H55N11O7 | 849.994 | 8 / 8 | 0.4 | No |
467202 | ![]() | C51H66N12O9 | 991.164 | 10 / 9 | 1.0 | No |
35309 | ![]() | C68H80N18O17 | 1421.5 | 21 / 20 | -2.4 | No |
35313 | ![]() | C68H80N18O17 | 1421.5 | 21 / 21 | -2.0 | No |
35367 | ![]() | C71H84N20O17 | 1489.58 | 22 / 22 | -2.9 | No |
35370 | ![]() | C71H84N20O17 | 1489.58 | 22 / 21 | -3.3 | No |
36345 | ![]() | C27H21ClN2O2 | 440.927 | 2 / 1 | 5.7 | No |
467502 | ![]() | C78H103N21O19S2 | 1702.93 | 23 / 25 | -0.9 | No |
522718 | ![]() | C80H107N23O15 | 1630.88 | 19 / 21 | 0.4 | No |
39994 | ![]() | C107H152N28O27S2 | 2326.68 | 33 / 32 | -6.4 | No |
40000 | ![]() | C107H152N28O27S2 | 2326.68 | 33 / 32 | -6.4 | No |
40004 | ![]() | C107H152N28O27S2 | 2326.68 | 33 / 32 | -6.4 | No |
40008 | ![]() | C107H152N28O27S2 | 2326.68 | 33 / 30 | -7.1 | No |
40013 | ![]() | C107H152N28O27S2 | 2326.68 | 33 / 32 | -6.4 | No |
40014 | ![]() | C107H152N28O27S2 | 2326.68 | 33 / 32 | -6.4 | No |
443273 | ![]() | C107H152N28O27S2 | 2326.68 | 33 / 32 | -6.4 | No |
443290 | ![]() | C41H46IN9O5 | 871.781 | 6 / 8 | 3.7 | No |
443293 | ![]() | C41H46IN9O5 | 871.781 | 6 / 8 | 3.7 | No |
41145 | ![]() | C30H40Cl2FN5O2 | 592.581 | 6 / 2 | 4.4 | No |
44413 | ![]() | C23H29N5O2 | 407.518 | 3 / 5 | 1.9 | Yes |
44417 | ![]() | C23H29N5O2 | 407.518 | 3 / 5 | 1.9 | Yes |
468542 | ![]() | C76H96N16O17 | 1505.7 | 18 / 18 | 2.3 | No |
46073 | ![]() | C73H86IN19O16 | 1612.51 | 19 / 19 | -2.1 | No |
46895 | ![]() | C67H83N19O16 | 1410.52 | 19 / 20 | -4.0 | No |
46898 | ![]() | C67H83N19O16 | 1410.52 | 19 / 19 | -4.4 | No |
49620 | ![]() | C37H45N9O5 | 695.825 | 6 / 7 | 1.2 | No |
469160 | ![]() | C54H66N12O9 | 1027.2 | 10 / 9 | 1.9 | No |
523031 | ![]() | C50H69N13O10 | 1012.18 | 13 / 11 | -0.2 | No |
51829 | ![]() | C30H36ClN9O4 | 622.127 | 6 / 7 | 1.2 | No |
52138 | ![]() | C24H31N5O2 | 421.545 | 3 / 5 | 2.3 | Yes |
52480 | ![]() | C20H22ClN5O2 | 399.879 | 3 / 3 | 1.7 | Yes |
53549 | ![]() | C49H73N11O5 | 896.195 | 7 / 9 | 7.9 | No |
469597 | ![]() | C84H114N22O21S2 | 1832.09 | 25 / 27 | -2.5 | No |
54367 | ![]() | C52H74N16O9 | 1067.27 | 12 / 13 | -0.4 | No |
56084 | ![]() | C35H42N12O5 | 710.8 | 8 / 9 | -0.3 | No |
58385 | ![]() | C34H43N11O5 | 685.79 | 7 / 9 | -0.3 | No |
58387 | ![]() | C34H43N11O5 | 685.79 | 7 / 9 | -0.3 | No |
58399 | ![]() | C34H43N11O5 | 685.79 | 7 / 9 | -0.3 | No |
58404 | ![]() | C34H43N11O5 | 685.79 | 7 / 9 | -0.3 | No |
58411 | ![]() | C34H43N11O5 | 685.79 | 7 / 9 | -0.3 | No |
58416 | ![]() | C34H43N11O5 | 685.79 | 7 / 9 | -0.3 | No |
58849 | ![]() | C67H84N18O16 | 1397.52 | 19 / 18 | -3.8 | No |
58852 | ![]() | C67H84N18O16 | 1397.52 | 19 / 17 | -4.2 | No |
444090 | ![]() | C51H69N17O8 | 1048.22 | 12 / 12 | 2.5 | No |
64601 | ![]() | C31H36N10O5 | 628.694 | 8 / 8 | 0.2 | No |
64655 | ![]() | C35H45N11O5 | 699.817 | 7 / 8 | 0.1 | No |
470883 | ![]() | C54H66N12O9 | 1027.2 | 10 / 9 | 1.9 | No |
470927 | ![]() | C51H68N12O8 | 977.181 | 10 / 9 | 1.6 | No |
65152 | ![]() | C35H43N11O5 | 697.801 | 7 / 8 | -0.2 | No |
65157 | ![]() | C35H43N11O5 | 697.801 | 7 / 8 | -0.2 | No |
65162 | ![]() | C35H43N11O5 | 697.801 | 7 / 8 | -0.2 | No |
65902 | ![]() | C39H50N12O6S | 814.967 | 9 / 9 | 0.0 | No |
66079 | ![]() | C46H67N11O5 | 854.114 | 7 / 9 | 6.2 | No |
66255 | ![]() | C77H93IN20O15S3 | 1761.8 | 21 / 20 | 1.3 | No |
70082 | ![]() | C44H55N11O7 | 849.994 | 8 / 8 | 0.4 | No |
70474 | ![]() | C66H82N16O14 | 1323.48 | 16 / 17 | -0.5 | No |
70830 | ![]() | C50H63N13O9S2 | 1054.26 | 14 / 12 | -0.2 | No |
444618 | ![]() | C50H71N17O8 | 1038.23 | 12 / 12 | 3.0 | No |
77644 | ![]() | C34H43N11O6 | 701.789 | 8 / 10 | -0.4 | No |
77647 | ![]() | C34H43N11O6 | 701.789 | 8 / 10 | -0.4 | No |
472624 | ![]() | C35H45N11O5 | 699.817 | 7 / 9 | -0.4 | No |
80091 | ![]() | C26H27N5O2 | 441.535 | 3 / 5 | 2.6 | Yes |
472831 | ![]() | C52H62N12O9 | 999.143 | 10 / 9 | 1.4 | No |
80548 | ![]() | C34H44N10O5 | 672.791 | 7 / 8 | 0.1 | No |
80552 | ![]() | C34H44N10O5 | 672.791 | 7 / 8 | 0.1 | No |
81409 | ![]() | C44H65N11O4 | 812.077 | 7 / 9 | 5.8 | No |
82015 | ![]() | C77H89N19O16 | 1536.68 | 19 / 19 | -1.5 | No |
473108 | ![]() | C54H66N12O9 | 1027.2 | 10 / 9 | 1.9 | No |
85416 | ![]() | C30H43ClN4O2 | 527.15 | 4 / 1 | 5.2 | No |
86754 | ![]() | C48H71N11O5 | 882.168 | 7 / 9 | 7.3 | No |
86759 | ![]() | C46H59N11O7 | 878.048 | 8 / 9 | 1.4 | No |
92926 | ![]() | C31H38FN9O5 | 635.701 | 8 / 7 | -0.1 | No |
93856 | ![]() | C34H42N10O5S | 702.835 | 8 / 8 | 0.9 | No |
474518 | ![]() | C52H70N12O8 | 991.208 | 10 / 9 | 1.9 | No |
96205 | ![]() | C54H71N15O9 | 1074.26 | 11 / 13 | 1.3 | No |
445498 | ![]() | C54H71N15O9 | 1074.26 | 11 / 13 | 1.3 | No |
524344 | ![]() | C54H71N15O9 | 1074.26 | 11 / 13 | 1.3 | No |
445640 | ![]() | C51H73N17O8 | 1052.26 | 12 / 12 | 3.7 | No |
101877 | ![]() | C30H40N10O5S | 652.775 | 8 / 8 | -0.4 | No |
106375 | ![]() | C31H41N11O5 | 647.741 | 8 / 8 | -1.2 | No |
106752 | ![]() | C36H44N10O5 | 696.813 | 7 / 8 | 1.1 | No |
106758 | ![]() | C36H44N10O5 | 696.813 | 7 / 8 | 1.1 | No |
107139 | ![]() | C29H36ClF3N4O2 | 565.078 | 7 / 1 | 5.0 | No |
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