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| Name | Melanocortin receptor 4 |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Mc4r |
| Synonym | MC4 receptor MC4-R |
| Disease | N/A for non-human GPCRs |
| Length | 332 |
| Amino acid sequence | MNSTHHHGMYTSLHLWNRSSHGLHGNASESLGKGHSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVSGVLFIIYSDSSAVIICLITMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGANMKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPLIYALRSQELRKTFKEIICFYPLGGICELPGRY |
| UniProt | P70596 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2700 |
| IUPHAR | 285 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 12399 |  RY-764 | C34H51FN4O3 | 582.805 | 5 / 2 | 5.4 | No |
| 18606 |  CHEMBL254757 | C31H40Cl3N3O2 | 593.03 | 3 / 1 | 6.4 | No |
| 20124 |  CHEMBL1209788 | C33H38ClF2N3O3 | 598.132 | 7 / 0 | 4.8 | No |
| 33383 |  D0I8SJ | C90H127N25O26S | 2007.21 | 31 / 27 | -10.1 | No |
| 558389 |  TAK-875 | C29H32O7S | 524.628 | 7 / 1 | 4.7 | No |
| 41139 |  CHEMBL393576 | C30H40Cl2FN5O2 | 592.581 | 6 / 2 | 4.4 | No |
| 76335 |  Ac-YR[CEHdFRWC]-NH2 | C60H79N19O13S2 | 1338.53 | 18 / 18 | -2.0 | No |
| 538345 |  CHEMBL3287569 | C27H25ClN2O3 | 460.958 | 4 / 1 | 5.3 | No |
| 107143 |  CHEMBL439560 | C29H36ClF3N4O2 | 565.078 | 7 / 1 | 5.0 | No |
| 553809 |  Setmelanotide | C49H68N18O9S2 | 1117.32 | 14 / 15 | -2.5 | No |
| 117743 |  THIQ | C33H41ClN6O2 | 589.181 | 5 / 2 | 5.9 | No |
| 562549 |  CHEMBL3930086 | C56H60CaN2O6S2 | 961.302 | 10 / 0 | N/A | No |
| 172825 |  MK-0489 | C34H44ClF2N3O2 | 600.192 | 5 / 1 | 5.8 | No |
| 206005 |  CHEMBL429854 | C31H40BrClFN3O2 | 621.032 | 4 / 1 | 5.9 | No |
| 206008 |  CHEMBL255286 | C31H40BrClFN3O2 | 621.032 | 4 / 1 | 5.9 | No |
| 263936 |  CHEMBL402769 | C32H41ClF3N3O2 | 592.144 | 6 / 1 | 6.0 | No |
| 270300 |  CHEMBL254589 | C31H40Cl2FN3O2 | 576.578 | 4 / 1 | 5.9 | No |
| 301472 |  CHEMBL497746 | C29H40ClFN4O2 | 531.113 | 5 / 1 | 5.0 | No |
| 341294 |  Ac-dR[CEHdFRWC]-NH2 | C51H70N18O11S2 | 1175.36 | 16 / 16 | -3.0 | No |
| 407248 |  CHEMBL368876 | C31H48FN5O3 | 557.755 | 6 / 3 | 3.9 | No |
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