Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	2-oxoglutarate receptor 1
Species	Rattus norvegicus (Rat)
Gene	Oxgr1
Synonym	P2Y purinoceptor 15 P2RY15 oxoglutarate receptor GPR99 GPR80 G-protein coupled receptor 80 G protein-coupled receptor 99 G protein-coupled receptor 80 Alpha-ketoglutarate receptor 1 2-oxoglutarate receptor 1 P2Y15 [ Show all ]
Disease	N/A for non-human GPCRs
Length	337
Amino acid sequence	MIETLDSPANDSDFLDYITALENCTDEQISFKMQYLPVIYSIIFLVGFPGNTVAISIYVFKMRPWKSSTIIMLNLALTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFGFHFNLYSSILFLTCFSLFRYIVIIHPMSCFSIQKTRWAVVACAGVWVISLVAVMPMTFLITSTTRTNRSACLDLTSSDDLTTIKWYNLILTATTFCLPLLIVTLCYTTIISTLTHGPRTHSCFKQKARRLTILLLLVFYVCFLPFHILRVIRIESRLLSISCSIESHIHEAYIVSRPLAALNTFGNLLLYVVVSNNFQQAFCSAVRCKAIGDLEQAKKDSCSNNP
UniProt	Q6Y1R5
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2325
IUPHAR	N/A
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
15274	CHEMBL608596	C17H22N6O4	374.401	8 / 4	-0.2	Yes
25271	CHEMBL608591	C17H24N6O4	376.417	8 / 4	0.3	Yes
26794	CHEMBL605866	C10H12N6O4	280.244	8 / 4	-1.5	Yes
29787	CHEMBL608888	C17H26N6O4	378.433	8 / 4	1.8	Yes
36153	CHEMBL609768	C21H34N6O4	434.541	8 / 4	4.0	Yes
41758	CHEMBL2070507	C14H18N6O4	334.336	8 / 4	-0.1	Yes
47555	CHEMBL608000	C20H26N6O4	414.466	8 / 4	1.6	Yes
74737	Adenosine-5'-(N-methoxy)carboxamide hydrate	C11H14N6O5	310.27	9 / 4	-1.0	Yes
93341	CHEMBL608293	C14H20N6O5	352.351	9 / 4	0.3	Yes
95376	CHEMBL608895	C14H20N6O4	336.352	8 / 4	0.3	Yes
95892	CHEMBL609775	C14H19N7O5	365.35	9 / 5	-1.7	Yes
111993	CHEMBL1791423	C12H13N5O4	291.267	8 / 4	-0.9	Yes
121026	CHEMBL2113492	C15H22N6O4	350.379	8 / 4	0.7	Yes
124485	CHEMBL608587	C12H16N6O5	324.297	9 / 4	-0.6	Yes
136999	CHEMBL612154	C20H32N6O4	420.514	8 / 4	3.4	Yes
140855	BRN 0587969	C15H20N6O4	348.363	8 / 4	0.2	Yes
145778	NECA	C12H16N6O4	308.298	8 / 4	-0.7	Yes
153141	CHEMBL608595	C10H12N6O5	296.243	9 / 5	-1.5	Yes
174592	CHEMBL609487	C20H31N7O5	449.512	9 / 5	0.8	Yes
175193	CHEMBL609773	C17H24N6O4	376.417	8 / 4	1.3	Yes
178903	CHEMBL2113436	C14H20N6O4	336.352	8 / 4	-0.1	Yes
183687	CHEMBL2113489	C16H22N6O4	362.39	8 / 4	0.8	Yes
193664	CHEMBL608003	C19H22N6O6	430.421	10 / 4	-0.5	Yes
201889	CHEMBL608296	C18H28N6O4	392.46	8 / 4	2.4	Yes
206170	CHEMBL609186	C14H20N6O4	336.352	8 / 4	0.2	Yes
217272	50908-62-8	C13H16N6O4	320.309	8 / 4	-0.5	Yes
246517	CHEMBL609776	C18H29N7O4	407.475	9 / 5	0.5	Yes
263047	5'-N-methylcarboxamidoadenosine	C11H14N6O4	294.271	8 / 4	-1.1	Yes
271351	CHEMBL609179	C19H24N6O4	400.439	8 / 4	1.1	Yes
278081	CHEMBL609774	C20H26N6O4	414.466	8 / 4	1.3	Yes
294183	CHEMBL607719	C16H24N6O4	364.406	8 / 4	1.3	Yes
342864	Adenosine-5'-(N-propyl)carboxamide	C13H18N6O4	322.325	8 / 4	-0.2	Yes
350589	CHEMBL609769	C19H30N6O4	406.487	8 / 4	2.9	Yes
352083	CHEMBL607717	C17H18N6O4	370.369	8 / 4	0.4	Yes
352084	BRN 0591237	C17H18N6O4	370.369	8 / 4	0.4	Yes
352556	CHEMBL609485	C22H36N6O4	448.568	8 / 4	4.5	Yes
404864	CHEMBL129903	C12H17N7O4	323.313	9 / 5	-2.0	Yes
429200	CHEMBL608893	C18H26N6O4	390.444	8 / 4	1.8	Yes