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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS002157455
Molecular formula	C23H29N5O2S2
IUPAC name	4-[4-(benzenesulfonyl)piperazin-1-yl]-5,6-dimethyl-2-(pyrrolidin-1-ylmethyl)thieno[2,3-d]pyrimidine
Molecular weight	471.638
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	3.8
Synonyms	HMS3054K23 1-(benzenesulfonyl)-4-{5,6-dimethyl-2-[(pyrrolidin-1-yl)methyl]thieno[2,3-d]pyrimidin-4-yl}piperazine MolPort-004-179-619 ZINC9789675 MCULE-1473563835 920952-68-7 SMR001239944 CHEMBL1727874 AKOS034151601 Z31097880 [ Show all ]
Inchi Key	AALMOIACVXSIMR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H29N5O2S2/c1-17-18(2)31-23-21(17)22(24-20(25-23)16-26-10-6-7-11-26)27-12-14-28(15-13-27)32(29,30)19-8-4-3-5-9-19/h3-5,8-9H,6-7,10-16H2,1-2H3
PubChem CID	16308431
ChEMBL	CHEMBL1727874
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
306	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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