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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL216192
Molecular formula	C28H32N4O3
IUPAC name	4-(3,4-dimethylphenoxy)-3-(phenylcarbamoylamino)-N-(2-pyrrolidin-1-ylethyl)benzamide
Molecular weight	472.589
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	4.5
Synonyms	BDBM50192518 SCHEMBL5150831 1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)-3-phenylurea
Inchi Key	AENNLOUNPCFAFV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H32N4O3/c1-20-10-12-24(18-21(20)2)35-26-13-11-22(27(33)29-14-17-32-15-6-7-16-32)19-25(26)31-28(34)30-23-8-4-3-5-9-23/h3-5,8-13,18-19H,6-7,14-17H2,1-2H3,(H,29,33)(H2,30,31,34)
PubChem CID	11236807
ChEMBL	CHEMBL216192
IUPHAR	N/A
BindingDB	50192518
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3661	Melanin-concentrating hormone receptor 1	P97639	Mchr1	Rattus norvegicus (Rat)	353
3662	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
3663	Melanin-concentrating hormone receptor 1	Q8JZL2	Mchr1	Mus musculus (Mouse)	353

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