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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL498519
Molecular formula	C25H24ClNO4
IUPAC name	4-[[(7S)-7-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydronaphthalen-2-yl]oxy]benzoic acid
Molecular weight	437.92
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	2.5
Synonyms	BDBM50272766 4-[((7S)-7-{[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino}-5,6,7,8-tetrahydro-2-naphthalenyl)oxy]benzoic Acid
Inchi Key	AGTKWPGCGIAEEZ-URXFXBBRSA-N
Inchi ID	InChI=1S/C25H24ClNO4/c26-20-3-1-2-18(12-20)24(28)15-27-21-8-4-16-5-11-23(14-19(16)13-21)31-22-9-6-17(7-10-22)25(29)30/h1-3,5-7,9-12,14,21,24,27-28H,4,8,13,15H2,(H,29,30)/t21-,24-/m0/s1
PubChem CID	24949887
ChEMBL	CHEMBL498519
IUPHAR	N/A
BindingDB	50272766
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5189	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
5188	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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