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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL225492
Molecular formula	C21H22ClN3
IUPAC name	N-[1-[(4-chlorophenyl)methyl]piperidin-3-yl]isoquinolin-5-amine
Molecular weight	351.878
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.8
Synonyms	5-Isoquinolinamine, N-[1-[(4-chlorophenyl)methyl]-3-piperidinyl]- DTXSID30438736 AKOS030556383 SCHEMBL3185054 N-(1-(4-chlorobenzyl)piperidin-3-yl)isoquinolin-5-amine BDBM50197902 CTK1J3393 675133-20-7 N-[1-(4-chlorobenzyl)-3-piperidyl]-N-(5-isoquinolyl)amine [ Show all ]
Inchi Key	AHBYTGBWKOEDEE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22ClN3/c22-18-8-6-16(7-9-18)14-25-12-2-4-19(15-25)24-21-5-1-3-17-13-23-11-10-20(17)21/h1,3,5-11,13,19,24H,2,4,12,14-15H2
PubChem CID	10360623
ChEMBL	CHEMBL225492
IUPHAR	N/A
BindingDB	50197902
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5419	C-C chemokine receptor type 2	P41597	CCR2	Homo sapiens (Human)	374

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