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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL46060
Molecular formula	C26H27Cl3N4O3
IUPAC name	1-[7-chloro-3-(3,4-dichlorophenyl)-2-oxo-4-(2-piperidin-2-ylethoxy)-1H-quinolin-6-yl]-3-cyclopropylurea
Molecular weight	549.877
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	4.9
Synonyms	BDBM50090566 1-[7-Chloro-3-(3,4-dichloro-phenyl)-2-oxo-4-(2-piperidin-2-yl-ethoxy)-1,2-dihydro-quinolin-6-yl]-3-cyclopropyl-urea
Inchi Key	ASEOTCOKDIUIKD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H27Cl3N4O3/c27-18-7-4-14(11-19(18)28)23-24(36-10-8-15-3-1-2-9-30-15)17-12-22(33-26(35)31-16-5-6-16)20(29)13-21(17)32-25(23)34/h4,7,11-13,15-16,30H,1-3,5-6,8-10H2,(H,32,34)(H2,31,33,35)
PubChem CID	44292733
ChEMBL	CHEMBL46060
IUPHAR	N/A
BindingDB	50090566
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
13069	Gonadotropin-releasing hormone receptor	P30969	Gnrhr	Rattus norvegicus (Rat)	327

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