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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL474474
Molecular formula	C30H29ClN6O3
IUPAC name	3-[4-[[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]carbamoyl]phenyl]benzamide
Molecular weight	557.051
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	3.2
Synonyms	BDBM50412986
Inchi Key	BOUOJMVWXKOEJX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H29ClN6O3/c1-19-24(18-37-30(40)27(31)26(17-34-37)36-14-12-33-13-15-36)6-3-7-25(19)35-29(39)21-10-8-20(9-11-21)22-4-2-5-23(16-22)28(32)38/h2-11,16-17,33H,12-15,18H2,1H3,(H2,32,38)(H,35,39)
PubChem CID	25209357
ChEMBL	CHEMBL474474
IUPHAR	N/A
BindingDB	50412986
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
29145	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
29146	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
29147	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
29144	Mas-related G-protein coupled receptor member X1	Q96LB2	MRGPRX1	Homo sapiens (Human)	322

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