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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1819611
Molecular formula	C27H28N2O5
IUPAC name	2-[4-methyl-3-[[2-methyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid
Molecular weight	460.53
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.5
Synonyms	BDBM50351481 SCHEMBL2188511
Inchi Key	BXGGCTPCRSAPDB-NRFANRHFSA-N
Inchi ID	InChI=1S/C27H28N2O5/c1-17-8-9-19(14-26(30)31)13-23(17)28-27(32)22-11-10-20(12-18(22)2)33-16-21-15-29(3)24-6-4-5-7-25(24)34-21/h4-13,21H,14-16H2,1-3H3,(H,28,32)(H,30,31)/t21-/m0/s1
PubChem CID	53494965
ChEMBL	CHEMBL1819611
IUPHAR	N/A
BindingDB	50351481
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
35050	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
35047	Prostaglandin D2 receptor	P70263	Ptgdr	Mus musculus (Mouse)	357
35049	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
35053	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
35046	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
35048	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513
35051	Prostaglandin F2-alpha receptor	P43117	Ptgfr	Mus musculus (Mouse)	366
35052	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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