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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL39784
Molecular formula	C24H35F3O5
IUPAC name	7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pentyl]cyclopentyl]heptanoic acid
Molecular weight	460.534
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	4.8
Synonyms	HMS3648N07 9.alpha.,11.alpha.,15S-Trihydroxy-17-trifluoromethylphenyl-18,19,20-trinor-prostan-1-oic acid SR-01000946455-1 MolPort-027-640-905 7-[(1R)-2beta-[(3R)-3-Hydroxy-5-[3-(trifluoromethyl)phenyl]pentyl]-3alpha,5alpha-dihydroxycyclopentane-1alpha-yl]heptanoic acid BDBM50090140 ZINC29327528 DSVAWVBHUBDAPY-AHJNKEMKSA-N 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F1.alpha. 7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-(3-trifluoromethyl-phenyl)-pentyl]-cyclopentyl}-heptanoic acid SR-01000946455 [ Show all ]
Inchi Key	DSVAWVBHUBDAPY-AHJNKEMKSA-N
Inchi ID	InChI=1S/C24H35F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h5-7,14,18-22,28-30H,1-4,8-13,15H2,(H,31,32)/t18-,19+,20+,21-,22+/m0/s1
PubChem CID	10389527
ChEMBL	CHEMBL39784
IUPHAR	N/A
BindingDB	50090140
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
67994	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
67996	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
67993	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
67995	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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