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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	N-cyclohexyl-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetamide
Molecular formula	C15H21N5O3
IUPAC name	N-cyclohexyl-2-(1,3-dimethyl-2,6-dioxopurin-7-yl)acetamide
Molecular weight	319.365
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	0.8
Synonyms	HMS2969B11 Oprea1_102300 Z19358327 AC1LFBKM MolPort-000-804-699 SMR000711000 N-cyclohexyl-2-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-yl)acetamide ST50719036 2-(1,3-dimethyl-2,6-dioxo(1,3,7-trihydropurin-7-yl))-N-cyclohexylacetamide MCULE-4973234518 Oprea1_402681 ZINC263593 AKOS000677429 SR-01000432240 CHEMBL1541812 N-cyclohexyl-2-(1,3-dimethyl-2,6-dioxopurin-7-yl)acetamide STK090688 41838-16-8 MLS001079022 SCHEMBL10279695 BAS 01129982 N-Cyclohexyl-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-purin-7-yl)-acetamide SR-01000432240-1 [ Show all ]
Inchi Key	FQXXUVFUWQGLPR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H21N5O3/c1-18-13-12(14(22)19(2)15(18)23)20(9-16-13)8-11(21)17-10-6-4-3-5-7-10/h9-10H,3-8H2,1-2H3,(H,17,21)
PubChem CID	775376
ChEMBL	CHEMBL1541812
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
473423	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
85188	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757
85189	Relaxin receptor 2	Q8WXD0	RXFP2	Homo sapiens (Human)	754
85190	Vasopressin V1b receptor	P47901	AVPR1B	Homo sapiens (Human)	424

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