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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL271574
Molecular formula	C26H29NO3S
IUPAC name	4-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-2-propan-2-ylsulfanylbenzoic acid
Molecular weight	435.582
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	2.8
Synonyms	(R)-4''-(2-(2-hydroxy-2-phenylethylamino)ethyl)-3-(isopropylthio)biphenyl-4-carboxylic acid BDBM50236184 SCHEMBL5703871 4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)-3-(isopropylthio)-4-biphenyl-4-carboxylic acid
Inchi Key	FYONCJXSNAVJFY-DEOSSOPVSA-N
Inchi ID	InChI=1S/C26H29NO3S/c1-18(2)31-25-16-22(12-13-23(25)26(29)30)20-10-8-19(9-11-20)14-15-27-17-24(28)21-6-4-3-5-7-21/h3-13,16,18,24,27-28H,14-15,17H2,1-2H3,(H,29,30)/t24-/m0/s1
PubChem CID	11453340
ChEMBL	CHEMBL271574
IUPHAR	N/A
BindingDB	50236184
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
90404	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
90406	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
90405	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
90407	Beta-3 adrenergic receptor	O02662	ADRB3	Canis lupus familiaris (Dog)	405

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