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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	L-162782
Molecular formula	C32H40N4O4S
IUPAC name	butyl N-[2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]phenyl]-4-(2-methylpropyl)phenyl]sulfonylcarbamate
Molecular weight	576.756
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	7.5
Synonyms	D0Z7AF SCHEMBL9133104 BDBM50141059 CHEMBL289614 N-Butyloxycarbonyl-4''-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-5-isobutyl-biphenyl-2-sulfonic acid amide butyl (4'-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)-5-isobutyl-[1,1'-biphenyl]-2-yl)sulfonylcarbamate [ Show all ]
Inchi Key	GABMQILPAPONQS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H40N4O4S/c1-7-9-16-40-32(37)35-41(38,39)28-15-12-25(17-21(3)4)19-27(28)26-13-10-24(11-14-26)20-36-29(8-2)34-30-22(5)18-23(6)33-31(30)36/h10-15,18-19,21H,7-9,16-17,20H2,1-6H3,(H,35,37)
PubChem CID	10031067
ChEMBL	CHEMBL289614
IUPHAR	N/A
BindingDB	50141059
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
91432	Type-1 angiotensin II receptor	P30555	AGTR1	Sus scrofa (Pig)	359
445348	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
91431	Type-1A angiotensin II receptor	P25095	Agtr1	Rattus norvegicus (Rat)	359
91433	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363

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