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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL62868
Molecular formula	C19H32O5S
IUPAC name	3-[3-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]propylsulfanyl]propanoic acid
Molecular weight	372.52
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	2.2
Synonyms	(11R,13E,15S)-9-Oxo-11,15-dihydroxy-4-thiaprosta-13-ene-1-oic acid BDBM50101863 3-{(S)-3-[(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1-enyl)-5-oxo-cyclopentyl]-propylsulfanyl}-propionic acid
Inchi Key	GEGZUKCXRBOEAP-MAEOAUKBSA-N
Inchi ID	InChI=1S/C19H32O5S/c1-2-3-4-6-14(20)8-9-16-15(17(21)13-18(16)22)7-5-11-25-12-10-19(23)24/h8-9,14-16,18,20,22H,2-7,10-13H2,1H3,(H,23,24)/b9-8+/t14-,15+,16+,18+/m0/s1
PubChem CID	44304474
ChEMBL	CHEMBL62868
IUPHAR	N/A
BindingDB	50101863
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
94336	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
94337	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
94338	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
94335	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
94334	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513

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