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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL482627
Molecular formula	C27H27ClN2O5
IUPAC name	5-[3-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]phenoxy]-2-(2-oxopyrrolidin-1-yl)benzoic acid
Molecular weight	494.972
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	1.4
Synonyms	BDBM50264587 (R)-5-(3-(2-(2-(3-chlorophenyl)-2-hydroxyethylamino)ethyl)phenoxy)-2-(2-oxopyrrolidin-1-yl)benzoic acid
Inchi Key	JQIVPXQYQMWJIR-VWLOTQADSA-N
Inchi ID	InChI=1S/C27H27ClN2O5/c28-20-6-2-5-19(15-20)25(31)17-29-12-11-18-4-1-7-21(14-18)35-22-9-10-24(23(16-22)27(33)34)30-13-3-8-26(30)32/h1-2,4-7,9-10,14-16,25,29,31H,3,8,11-13,17H2,(H,33,34)/t25-/m0/s1
PubChem CID	44579941
ChEMBL	CHEMBL482627
IUPHAR	N/A
BindingDB	50264587
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
157322	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
157320	Beta-3 adrenergic receptor	O02662	ADRB3	Canis lupus familiaris (Dog)	405
157321	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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