Zhang Lab

University of Michigan

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001219965
Molecular formula	C22H26N4O6
IUPAC name	1-N',6-N'-bis(2-phenoxyacetyl)hexanedihydrazide
Molecular weight	442.472
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	1.9
Synonyms	1-N'',6-N''-bis(2-phenoxyacetyl)hexanedihydrazide N'-{6-oxo-6-[2-(phenoxyacetyl)hydrazino]hexanoyl}-2-phenoxyacetohydrazide SR-01000321189 STK031740 AKOS000487598 KB-104069 N-(2-phenoxyacetylamino)-N'-(2-phenoxyacetylamino)hexane-1,6-diamide BAS 00632602 N1'',N6''-bis(2-phenoxyethanoyl)hexanedihydrazide SR-01000321189-1 1-N',6-N'-bis(2-phenoxyacetyl)hexanedihydrazide CHEMBL195258 N'1,N'6-bis(phenoxyacetyl)hexanedihydrazide ZINC8396581 AN-329/11284456 KS-00004CQZ N1'',N6''-bis(1-oxo-2-phenoxyethyl)hexanedihydrazide BDBM75668 MolPort-001-026-535 SMR000608010 ST040593 AC1MJK5S cid_3113773 N'~1~,N'~6~-bis(phenoxyacetyl)hexanedihydrazide ARONIS021213 MCULE-7355707109 N1'',N6''-bis(2-phenoxyacetyl)adipohydrazide [ Show all ]
Inchi Key	JRJOEGZZOWPWDI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26N4O6/c27-19(23-25-21(29)15-31-17-9-3-1-4-10-17)13-7-8-14-20(28)24-26-22(30)16-32-18-11-5-2-6-12-18/h1-6,9-12H,7-8,13-16H2,(H,23,27)(H,24,28)(H,25,29)(H,26,30)
PubChem CID	3113773
ChEMBL	CHEMBL195258
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
158080	G-protein coupled receptor 182	O15218	GPR182	Homo sapiens (Human)	404

zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218