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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Pyrathiazine
Molecular formula	C18H20N2S
IUPAC name	10-(2-pyrrolidin-1-ylethyl)phenothiazine
Molecular weight	296.432
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.7
Synonyms	CAS-84-08-2 KJKJUXGEMYCCJN-UHFFFAOYSA-N Oprea1_320249 Paratiazina [INN-Spanish] Pyrrolazoate (Salt/Mix) SR-01000945030 10-(2-(1-Pyrrolidinyl)ethyl)phenothiazine 2305SQ56Z2 CHEMBL1887666 N-(.beta.-Pyrrolidinoethyl)phenothiazine Parathiazine (pharmaceutical) Phenothiazine, 10-(2-(1-pyrrolidinyl)ethyl)- Pyrrolidine, 1-[2-(10H-phenothiazin-10-yl)ethyl]- UNII-2305SQ56Z2 10-[2-(1-Pyrrolidinyl)ethyl]-10H-phenothiazine 84-08-2 DSSTox_RID_81479 NCIOpen2_008241 Parathiazinum [INN-Latin] Pyrathiazine [INN] Rolazote (Salt/Mix) 10-[2-(pyrrolidin-1-yl)ethyl]-10H-phenothiazine AKOS024338465 CAS_10646 LS-105660 Parathiazine PDSP1_000148 Pyrrolazote (Salt/Mix) SR-01000945030-1 10-(2-(1-Pyrrolidyl)ethyl)phenothiazine 522-25-8 (mono-hydrochloride) DSSTox_CID_26252 N-(beta-Pyrrolidinoethyl)phenothiazine Parathiazine [INN] Phenothiazine, 10-[2-(1-pyrrolidinyl)ethyl]- Pyrrolidino-aethyl-phenthiazin ZINC2004 10-[2-(1-Pyrrolidinyl)ethyl]-10H-phenothiazine # AC1L1VN7 BDBM81472 DTXSID2046252 NSC_10646 Paratiazina Pyrathiazinum SCHEMBL2110244 10H-Phenothiazine, 10-[2-(1-pyrrolidinyl)ethyl]- CHEBI:135253 MCULE-1475912489 Parathiazine (DCI) PDSP2_000147 Pyrrolidine, 1-(2-phenothiazin-10-ylethyl)- Tox21_111927 10-(2-pyrrolidin-1-ylethyl)phenothiazine DSSTox_GSID_46252 NCGC00160599-01 Parathiazinum Pyrrolidino-aethyl-phenthiazin [German] 10-[2-(1-Pyrrolidinyl)ethyl]phenothiazine AC1Q28UQ [ Show all ]
Inchi Key	KJKJUXGEMYCCJN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H20N2S/c1-3-9-17-15(7-1)20(14-13-19-11-5-6-12-19)16-8-2-4-10-18(16)21-17/h1-4,7-10H,5-6,11-14H2
PubChem CID	10646
ChEMBL	N/A
IUPHAR	N/A
BindingDB	81472
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
170570	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486

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