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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ethyl 2-amino-4,5-diphenylthiophene-3-carboxylate
Molecular formula	C19H17NO2S
IUPAC name	ethyl 2-amino-4,5-diphenylthiophene-3-carboxylate
Molecular weight	323.41
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.3
Synonyms	AC1N2G1O Oprea1_587100 4815-43-4 AKOS026670593 ZINC3064516 CHEMBL291935 Ethyl 2-Amino-4,5-diphenylthiophene-3-carboxylate, 97%, AldrichCPR BDBM50299476 2-Amino-4,5-diphenyl-thiophene-3-carboxylic acid ethyl ester D0V2VU [ Show all ]
Inchi Key	KZDXAPZNXDJJMB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H17NO2S/c1-2-22-19(21)16-15(13-9-5-3-6-10-13)17(23-18(16)20)14-11-7-4-8-12-14/h3-12H,2,20H2,1H3
PubChem CID	3997004
ChEMBL	CHEMBL291935
IUPHAR	N/A
BindingDB	50299476
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
181713	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
181714	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877

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