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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431111
Molecular formula	C29H32N4O2
IUPAC name	4-[4-(2,6-dimethylphenyl)piperazin-1-yl]-6-ethoxy-7-methoxy-2-phenylquinazoline
Molecular weight	468.601
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	6.3
Synonyms	BDBM50440750
Inchi Key	LTTBBFCZVUSRDT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H32N4O2/c1-5-35-26-18-23-24(19-25(26)34-4)30-28(22-12-7-6-8-13-22)31-29(23)33-16-14-32(15-17-33)27-20(2)10-9-11-21(27)3/h6-13,18-19H,5,14-17H2,1-4H3
PubChem CID	73356947
ChEMBL	CHEMBL2431111
IUPHAR	N/A
BindingDB	50440750
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
196208	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
196207	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
196206	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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