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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	periciazine
Molecular formula	C21H23N3OS
IUPAC name	10-[3-(4-hydroxypiperidin-1-yl)propyl]phenothiazine-2-carbonitrile
Molecular weight	365.495
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.5
Synonyms	Piperocyanomazine 3405M6FD73 RP 8909 AN-18883 SPECTRUM1503936 C21H23N3OS Tox21_111417 D01485 EINECS 220-071-3 KBio1_000874 LUALIOATIOESLM-UHFFFAOYSA-N Neuleptil 10-[3-(4-Hydroxy-1-piperidinyl)propyl]-10H-phenothiazine-2-carbonitrile # Propericiazine (JAN) 6909 RP SCHEMBL148422 Bayer 1409 Spectrum4_000210 CHEBI:31981 ZINC538159 DivK1c_000874 GTPL9216 KBio2_007230 NCGC00095086-03 NSC-758641 1-(3-(2-cyano-10-phenothiazinyl)propyl)-4-piperidino Periciazinum [INN-Latin] 10-[3-(4-hydroxypiperidin-1-yl)propyl]phenothiazine-2-carbonitrile 2-Cyano-10-(3-(4-hydroxypiperidino)propyl)phenothiazine PubChem2346 AC1Q4RQI SKF-20716 BRN 0576739 SR-01000872777 Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazine [French] DSSTox_RID_81221 IC 6002 KBioSS_002094 Neulactil Periciazina 10-(3-(4-Hydroxypiperidino)propyl)phenothiazine-2-carbonitrile Phenothiazine-2-carbonitrile, 10-(3-(4-hydroxypiperidino)propyl)- Properazine 4-Piperidinol, 1-(3-(2-cyano-10-phenothiazinyl)propyl)- RP-8909 Aolept Spectrum2_001604 CAS-2622-26-6 UNII-3405M6FD73 F.I. 6145 KBio2_002094 NCGC00095086-01 Neuleptil (TN) Periciazine [INN] 10-[3-(4-hydroxy-1-piperidyl)propyl]phenothiazine-2-carbonitrile propericiazine(jan) SKF 20,716 BDBM50346422 Spectrum5_001747 CHEMBL251940 DSSTox_CID_25910 HMS1922M18 KBio3_001556 Nelactil NSC758641 10-(3-(4-Hydroxypiperidin-1-yl)propyl)-10H-phenothiazine-2-carbonitrile PERICYAZINE 10H-Phenothiazine-2-carbonitrile, 10-[3-(4-hydroxy-1-piperidinyl)propyl]- 2622-26-6 RP 8908 AKOS030527553 SPBio_001607 BSPBio_002336 SR-01000872777-1 D00AWT DTXSID5045910 IDI1_000874 LS-105273 Neulactil (TN) Periciazina [INN-Spanish] 10-[3-(4-Hydroxy-1-piperidinyl)propyl]-10H-phenothiazine-2-carbonitrile Phenothiazine-2-carbonitrile, 10-[3-(4-hydroxypiperidino)propyl]- Propericiazine SBI-0051867.P002 API0003549 Spectrum3_000748 CCG-39062 WH 7508 DB01608 FT-0673633 KBio2_004662 NCGC00095086-02 NINDS_000874 Periciazinum 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine propericyazine AC1L1IV8 SKF 20716 BRD-K89669299-001-02-7 Spectrum_001614 Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazine DSSTox_GSID_45910 HMS502L16 KBioGR_000819 Nemactil Periciazin 10-(3-(4-hydroxypiperidino)propyl)-phenothiazine-2-carbonitril Pharmakon1600-01503936 [ Show all ]
Inchi Key	LUALIOATIOESLM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H23N3OS/c22-15-16-6-7-21-19(14-16)24(18-4-1-2-5-20(18)26-21)11-3-10-23-12-8-17(25)9-13-23/h1-2,4-7,14,17,25H,3,8-13H2
PubChem CID	4747
ChEMBL	N/A
IUPHAR	9216
BindingDB	50346422
DrugBank	DB01608
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
196386	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
196385	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
196383	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
196382	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
196384	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446

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