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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL315444
Molecular formula	C25H28N6O2
IUPAC name	2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,3-diazaspiro[4.4]nonane-1,4-dione
Molecular weight	444.539
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.3
Synonyms	BDBM50089990 2-butyl-3-[2''-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,3-diaza-spiro[4.4]nonane-1,4-dione 7-butyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-7,8-diazaspiro[4.4]nonane-6,9-dione 3-Butyl-2-[2'-(1H-tetrazole-5-yl)-4-biphenylylmethyl]-2,3-diazaspiro[4.4]nonane-1,4-dione AC1NRWTL 2-Butyl-3-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,3-diaza-spiro[4.4]nonane-1,4-dione [ Show all ]
Inchi Key	LVYNCTNJHNBWOC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H28N6O2/c1-2-3-16-30-23(32)25(14-6-7-15-25)24(33)31(30)17-18-10-12-19(13-11-18)20-8-4-5-9-21(20)22-26-28-29-27-22/h4-5,8-13H,2-3,6-7,14-17H2,1H3,(H,26,27,28,29)
PubChem CID	5249743
ChEMBL	CHEMBL315444
IUPHAR	N/A
BindingDB	50089990
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
197813	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
197814	Type-1A angiotensin II receptor	P25095	Agtr1	Rattus norvegicus (Rat)	359

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