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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431132
Molecular formula	C23H26N4O4S
IUPAC name	4-[4-(benzenesulfonyl)piperazin-1-yl]-2-cyclopropyl-6,7-dimethoxyquinazoline
Molecular weight	454.545
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	3.1
Synonyms	MLS004254801 SCHEMBL15818954 BDBM50440740 MLS-0469656.0001 1-(2-cyclopropyl-6,7-dimethoxyquinazolin-4-yl)-4-(phenylsulfonyl)piperazine SMR003080914 [ Show all ]
Inchi Key	MHFYXZJTMQZPBR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H26N4O4S/c1-30-20-14-18-19(15-21(20)31-2)24-22(16-8-9-16)25-23(18)26-10-12-27(13-11-26)32(28,29)17-6-4-3-5-7-17/h3-7,14-16H,8-13H2,1-2H3
PubChem CID	56593283
ChEMBL	CHEMBL2431132
IUPHAR	N/A
BindingDB	50440740
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
205388	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
205389	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
205387	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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