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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL507506
Molecular formula	C26H30N2O4
IUPAC name	4-[4-[(2R)-2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]propyl]phenyl]-2-propoxybenzoic acid
Molecular weight	434.536
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	1.7
Synonyms	4'-[(2R)-2-[[(2R)-2-Hydroxy-2-(3-pyridyl)ethyl]amino]propyl]-3-propoxy-4-biphenylcarboxylic acid BDBM50243392 4-((2R)-2-{[(2R)-2-Hydroxy-2-(3-pyridinyl)ethyl]amino}propyl)-3-propoxy-4-biphenylcarboxylic acid
Inchi Key	PAMFWLSSFZPHMC-KOSHJBKYSA-N
Inchi ID	InChI=1S/C26H30N2O4/c1-3-13-32-25-15-21(10-11-23(25)26(30)31)20-8-6-19(7-9-20)14-18(2)28-17-24(29)22-5-4-12-27-16-22/h4-12,15-16,18,24,28-29H,3,13-14,17H2,1-2H3,(H,30,31)/t18-,24+/m1/s1
PubChem CID	44560793
ChEMBL	CHEMBL507506
IUPHAR	N/A
BindingDB	50243392
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
254892	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
254893	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
254890	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
254891	Beta-3 adrenergic receptor	O02662	ADRB3	Canis lupus familiaris (Dog)	405

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