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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL505346
Molecular formula	C13H17N7
IUPAC name	4-(4-methylpiperazin-1-yl)-6-pyrimidin-5-ylpyrimidin-2-amine
Molecular weight	271.328
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	0.1
Synonyms	ZINC40833598 6-(4-methylpiperazin-1-yl)-4,5'-bipyrimidin-2-amine MolPort-030-047-059 SCHEMBL2165762
Inchi Key	PAQJDMHAEFDKPF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H17N7/c1-19-2-4-20(5-3-19)12-6-11(17-13(14)18-12)10-7-15-9-16-8-10/h6-9H,2-5H2,1H3,(H2,14,17,18)
PubChem CID	25130229
ChEMBL	CHEMBL505346
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
255033	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391
255034	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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