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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431232
Molecular formula	C25H30N4O2
IUPAC name	2-cyclobutyl-6,7-dimethoxy-4-[4-(2-methylphenyl)piperazin-1-yl]quinazoline
Molecular weight	418.541
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	5.0
Synonyms	BDBM50440768 MLS-0454701.0001 SCHEMBL15821073
Inchi Key	QAHFFKCDOYHKTJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30N4O2/c1-17-7-4-5-10-21(17)28-11-13-29(14-12-28)25-19-15-22(30-2)23(31-3)16-20(19)26-24(27-25)18-8-6-9-18/h4-5,7,10,15-16,18H,6,8-9,11-14H2,1-3H3
PubChem CID	51035373
ChEMBL	CHEMBL2431232
IUPHAR	N/A
BindingDB	50440768
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
273363	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
273364	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
273365	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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