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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1957435
Molecular formula	C26H26N2O4S2
IUPAC name	2-[2-[(2R)-2-[(E,3S)-3-hydroxy-4-(3-phenylphenyl)but-1-enyl]-5-oxopyrrolidin-1-yl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Molecular weight	494.624
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.5
Synonyms	BDBM50366136 SCHEMBL10210671
Inchi Key	TZZLWYONQVXDRN-JEUBMUGFSA-N
Inchi ID	InChI=1S/C26H26N2O4S2/c29-22(16-18-5-4-8-20(15-18)19-6-2-1-3-7-19)11-9-21-10-12-24(30)28(21)13-14-33-26-27-23(17-34-26)25(31)32/h1-9,11,15,17,21-22,29H,10,12-14,16H2,(H,31,32)/b11-9+/t21-,22+/m0/s1
PubChem CID	57394893
ChEMBL	CHEMBL1957435
IUPHAR	N/A
BindingDB	50366136
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
331612	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
331613	Prostaglandin E2 receptor EP2 subtype	Q62928	Ptger2	Rattus norvegicus (Rat)	357
331616	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
331614	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
331615	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513
331617	Prostaglandin E2 receptor EP4 subtype	P43114	Ptger4	Rattus norvegicus (Rat)	488

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