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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL404372
Molecular formula	C9H10ClN3
IUPAC name	(4S)-5-chloro-4-methyl-1,4-dihydroquinazolin-2-amine
Molecular weight	195.65
Hydrogen bond acceptor	1
Hydrogen bond donor	2
XlogP	1.2
Synonyms	1005470-25-6 BDBM50371998 2-Quinazolinamine, 5-chloro-1,4-dihydro-4-methyl-, (4S)-
Inchi Key	XFMPGBXLGWZMQP-YFKPBYRVSA-N
Inchi ID	InChI=1S/C9H10ClN3/c1-5-8-6(10)3-2-4-7(8)13-9(11)12-5/h2-5H,1H3,(H3,11,12,13)/t5-/m0/s1
PubChem CID	44456033
ChEMBL	CHEMBL404372
IUPHAR	N/A
BindingDB	50371998
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
390518	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
390519	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
390515	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
390512	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
390516	5-hydroxytryptamine receptor 5A	P35364	Htr5a	Rattus norvegicus (Rat)	357
390517	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
390514	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
390513	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479

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